Human Immunodeficiency Virus (HIV) Combo Antigen/Antibody (HIV-1/O/2) by CIA, with Reflex to HIV-1 Antibody Confirmation by Western Blot
2006526
Ordering Recommendation
Mnemonic
HIV AGAB
Methodology
Qualitative Chemiluminescent Immunoassay /Qualitative Western Blot
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
- Patient Preparation
- Collect
- Serum separator tube (SST). Also acceptable: Lavender (EDTA), pink (K2EDTA).
- Specimen Preparation
- Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum or plasma to an ARUP Standard Transport Tube. Remove particulate material. (Min: 0.75 mL) Remove particulate material.
- Storage/Transport Temperature
- Refrigerated.
- Unacceptable Conditions
- Specimens containing particulate material. Severely hemolyzed or heat-inactivated specimens.
- Remarks
- Stability
- After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 8 months (avoid repeated freeze/thaw cycles)
Reference Interval
| Test Number | Components | Reference Interval |
|---|---|---|
| Human Immunodeficiency Virus (HIV) Combo Antigen/Antibody (HIV-1/O/2) by CIA | Negative | |
| 0020284 | Human Immunodeficiency Virus Type 1 (HIV-1) Antibody Confirmation by Western Blot | Negative |
Interpretive Data
This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).
Note
This fourth-generation screen test is for the simultaneous qualitative detection of Human Immunodeficiency Virus Type 1 (HIV-1) p24 antigen and antibodies to HIV Type 1 (HIV-1 groups M and O) and HIV Type 2 (HIV-2), Results of the screen cannot be used to distinguish between the presence of HIV-1 p24 antigen, HIV-1 antibody, or HIV-2 antibody.
If the HIV-1,2 Combo Antigen/Antibodies screen is repeatedly reactive, then the Human Immunodeficiency Virus Type 1 (HIV-1) Antibody Confirmation by Western Blot will be added. Additional charges apply.
Performed and Reported times indicated are for the screening portion of this test. Refer to Human Immunodeficiency Virus Type 1 (HIV-1) Antibody Confirmation by Western Blot (ARUP test code 0020284) for additional information regarding Performed or Reported times for the reflex portion of this test.
If the HIV-1,2 Combo Antigen/Antibodies screen is repeatedly reactive, then the Human Immunodeficiency Virus Type 1 (HIV-1) Antibody Confirmation by Western Blot will be added. Additional charges apply.
Performed and Reported times indicated are for the screening portion of this test. Refer to Human Immunodeficiency Virus Type 1 (HIV-1) Antibody Confirmation by Western Blot (ARUP test code 0020284) for additional information regarding Performed or Reported times for the reflex portion of this test.
Hotline History
View Hotline History
CPT Code(s)
87389; if reflexed, add 86689
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2006611 | HIV-1,2 Combo Antigen/Antibody | 56888-1 |
Aliases
- 4th generation HIV screen; HIV Ag/Ab combination screen
- Fourth generation HIV
- HIV 1,2 Combo Antigen/Antibody
- HIV Diagnosis
- HIV-1,2 Combo Antigen/Antibody