Viral Culture, Non-Respiratory
Ordering Recommendation

Generally, virus-specific testing (eg, antigen detection or molecular) is recommended.

Cell Culture
3-14 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Eye swab, lesion, stool, tissue (brain, colon, kidney, liver, etc.), or urine. 
Specimen Preparation
Fluid: Transfer 3 mL specimen to a sterile container. (Min: 0.5 mL) Also acceptable: Transfer to 3 mL viral transport media (ARUP Supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Stool: Transfer 1 mL stool to an unpreserved stool transport vial (ARUP supply #40910) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)
Swab or Tissue:
Place in 3 mL viral transport media (ARUP Supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. 
Storage/Transport Temperature
Unacceptable Conditions
Calcium alginate, eSwab, dry, or wood swabs. 
Specimen source preferred. 
Ambient: 2 hours; Refrigerated: 72 hours; Frozen: Unacceptable 
Reference Interval
Interpretive Data

Identification is billed separately from culture. Viruses that can be isolated by culture include: adenovirus, cytomegalovirus, enterovirus, herpes simplex virus, and varicella-zoster virus.  However, virus-specific tests are recommended and are listed below.

The following test is standard-of-care for diagnosing Adenovirus infection in tissue specimens:
Adenovirus by Qualitative PCR (ARUP test code 2007473)

The following tests are standard-of-care for diagnosing viral infection in CSF specimens:
Cytomegalovirus by PCR (ARUP test code 0060040)
Enterovirus Detection by RT-PCR (ARUP test code 0050249)
Epstein-Barr Virus by PCR (ARUP test code 0050246)
Herpes Simplex Virus by PCR (ARUP test code 0060041)
Varicella-Zoster Virus by PCR (ARUP test code 0060042)

The following tests are recommended for detecting a specific virus in specimens other than CSF. If a specific virus is suspected, please indicate the virus on the test request. 

1. Cytomegalovirus. Refer to Cytomegalovirus Rapid Culture (ARUP test code 0065004 ).
2. Human metapneumovirus (hMPV). hMPV can be detected by DFA staining or nucleic acid testing. Refer to Human Metapneumovirus by DFA (ARUP test code 0060779) and Respiratory Viruses DFA (ARUP test code 0060289), or Human Metapneumovirus by RT-PCR (ARUP test code 0060784).
3. Measles virus. Refer to Measles (Rubeola) Virus Culture (ARUP test code 0065055).
4. Mumps virus. Refer to Mumps Virus Culture (ARUP test code 0065056).
5. Respiratory syncytial virus (RSV). Refer to Respiratory Syncytial Virus DFA (ARUP test code 0060288 ).
6. Respiratory viruses. Refer to Respiratory Viruses DFA (ARUP test code 0060289); Viral Culture, Respiratory (ARUP test code 2006499); or Respiratory Viruses DFA with Reflex to Viral Culture, Respiratory (ARUP test code 0060281).
7. Varicella-zoster virus. Refer to Varicella-Zoster Virus DFA with Reflex to Varicella-Zoster Virus Culture (ARUP test code 0060282).
Hotline History
CPT Code(s)
87252; if definitive identification performed, add 87253
Component Test Code*Component Chart NameLOINC
2006498Viral Culture, Non-Respiratory6584-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Adenovirus Culture
  • CMV, Cytomegalovirus Culture, Varicella Zoster Culture
  • Coxsackie Virus (CSF & Rectal Swab)
  • Culture for Virus, Routine
  • Culture, Coxsackie Virus/Echovirus
  • Echovirus
  • Enterovirus
  • Herpes 1 and 2 (Culture)
  • Herpes or Herpes Simplex Virus Cult
  • Viral Culture, General
  • Viral Isolation
  • Virus (CSF)
  • Virus, Culture-Stool