Viral Culture, Non-Respiratory and Cytomegalovirus Rapid Culture
Ordering Recommendation
For best results, specify specimen source and suspected virus on order form. Molecular diagnostics are preferred for suspected invasive CMV.
Cell Culture/Immunofluorescence
Viral Culture: 3-16 days
Cytomegalovirus Rapid Culture: 1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Eye swab, lesion, tissue (brain, colon, kidney, liver, etc.), or urine.  
Specimen Preparation
Fluid: Transfer to sterile, leak-proof container.
Swabs or Tissue:
Place in viral transport media (ARUP Supply #12884). Available online through eSupply using ARUP Connect™or contact ARUP Client Services (800) 522-2787. Place each specimen in a separate, individually sealed bag.  
Storage/Transport Temperature
Unacceptable Conditions
Calcium alginate, eSwab, dry, or wood swabs.  
Specimen source preferred.  
Ambient: 2 hours; Refrigerated: 72 hours; Frozen: Unacceptable  
Reference Interval
Interpretive Data
Identification is billed separately from culture. Viruses that can be isolated include: adenovirus, cytomegalovirus, enterovirus, herpes simplex virus, and varicella-zoster virus. However, virus-specific tests are recommended for varicella-zoster virus (order Varicella-Zoster Virus DFA with Reflex to Varicella-Zoster Virus Culture, ARUP test code 0060282).

The following tests are standard of care for diagnosing viral infection in CSF specimens:
Cytomegalovirus by PCR (ARUP test code 0060040)
Enterovirus Detection by RT-PCR (ARUP test code 0050249)
Herpes Simplex Virus by PCR (ARUP test code 0060041)
Varicella-Zoster Virus by PCR (ARUP test code 0060042)

An ELISA test (Rotavirus & Adenovirus 40-41 Antigens, ARUP test code 0065067)) is available for enteric adenoviruses 40-41 and rotavirus in stool specimens. For measles virus culture, order Measles (Rubeola) Virus Culture (ARUP test code 0065055). For mumps virus culture, order Mumps Virus Culture (ARUP test code 0065056).

If a specific virus is suspected, please indicate which virus on the test request.
CPT Code(s)
87252; 87254; if definitive identification performed, add 87253
Component Test Code*Component Chart Name
2006496Viral Culture, Non-Resp and CMV Culture
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at
Cross References
  • adenovirus
  • CMV culture, HSV culture
  • CMV Rapid Culture
  • cytomegalovirus
  • enterovirus
  • herpes simplex virus
  • varicella-zoster virus
  • VZV culture