WT1 Mutation Detection by Sequencing
2005766
Ordering Recommendation
WT1 testing is appropriate for detecting mutations in exons 7 and 9 as well as for the presence of SNP rs16754 in cases of cytogenetically normal AML.
Mnemonic
WT1
Methodology
Polymerase Chain Reaction/Sequencing
Performed
Varies
Reported
12-14 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) OR bone marrow (EDTA).  
Specimen Preparation
Transport 5 mL whole blood (Min: 1 mL) OR 3 mL bone marrow (Min: 1 mL).  
Storage/Transport Temperature
Refrigerated  
Unacceptable Conditions
Serum or plasma. Specimens collected in anticoagulants other than EDTA. Frozen specimens. Clotted or severely hemolyzed specimens  
Remarks
  
Stability
Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
Refer to report

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
81479
Components
Component Test Code*Component Chart Name
2005767WT1 Mutation Results
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CN-AML prognostication
  • rs16754
  • WT1 exons 7, 9, SNP rs16754