Patients in the early stage of JEV infection may not have a detectable level of IgG antibody; IgG response may take several days to several weeks to develop. In the absence of detectable IgG antibody, testing for IgM-class antibody is strongly recommended. A positive result (5.0 IV or greater) indicates the presence of IgG antibody to a flavivirus
in the Japanese encephalitis serogroup or the dengue virus serogroup. Cross-species plaque reduction neutralization tests on paired acute and convalescent sera are an acceptable means of determining the flavivirus
causing the antibody production.
Compliance Statement D
: For laboratory tests using a manufactured RUO kit.
This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.