Japanese Encephalitis Virus Antibody, IgG by ELISA
Ordering Recommendation

Not recommended as a stand-alone test. Japanese Encephalitis Virus Antibodies, IgG and IgM by ELISA (2005689) is preferred.

Semi-Quantitative Enzyme-Linked Immunosorbent Assay
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated or heat-inactivated specimens. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles). 
Reference Interval
Effective May 21, 2018
Japanese Encephalitis Virus Antibody, IgG by ELISA
1.9 IV or lessNegative - No significant level of detectable Japanese encephalitis virus (JEV) IgG antibody.
2.0 - 5.0 IVEquivocal - Questionable presence of JEV IgG antibody. Repeat testing in 10-14 days may be helpful.
5.1 IV or greaterPositive - JEV IgG antibody detected, which may indicate a current or past infection.

Interpretive Data
Patients in the early stage of JEV infection may not have a detectable level of IgG antibody; IgG response may take several days to several weeks to develop. In the absence of detectable IgG antibody, testing for IgM-class antibody is strongly recommended. A positive result (5.1 IV or greater) indicates the presence of IgG antibody to a Flavivirus in the Japanese encephalitis serogroup or the dengue virus serogroup. Cross-species plaque reduction neutralization tests on paired acute and convalescent sera are an acceptable means of determining the Flavivirus causing the antibody production.

Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
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Component Test Code*Component Chart NameLOINC
2005688Japanese Encephalitis Virus Antibody IgG7934-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • JE Virus IgG