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Japanese Encephalitis Virus Antibody, IgM by ELISA
2005685
Ordering Recommendation

Not recommended as a stand-alone test. Panel that combines Japanese encephalitis virus IgG and IgM antibodies is preferred (2005689).

Mnemonic
JPN M
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Thu
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)  
Storage/Transport Temperature
Refrigerated  
Unacceptable Conditions
Contaminated or heat-inactivated specimens  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles)  
Reference Interval
Effective January 17, 2012
Japanese Encephalitis Virus Antibody, IgM by ELISA
3.9 IV or lessNegative - No significant level of detectable Japanese encephalitis virus (JEV) IgM antibody.
4.0 -6.0 IVEquivocal - Questionable presence of JEV IgM antibody. Repeat testing in 10-14 days may be helpful.
6.1 IV or greaterPositive - JEV IgM antibody detected, which may indicate a current or recent infection. A low IgM antibody level may occasionally persist for more than 12 months post-infection.

Interpretive Data
A positive result (6.1 IV or greater) indicates the presence of IgM antibody to a flavivirus in the Japanese encephalitis serogroup or the dengue virus serogroup. The best evidence of current infection is a significant change on two appropriately timed specimens with both tests performed in the same laboratory at the same time.


Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Note
CPT Code(s)
86790
Components
Component Test Code*Component Chart NameLOINC
2005686Japanese Encephalitis Virus Antibody IgM63562-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • JE Virus IgM