Feedback
Endomysial Antibody, IgG
2005501
Ordering Recommendation

• Acceptable single screening test for IgA-deficient individuals with suspected celiac disease. 
• Preferred screening test is Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgG (0056009).  (IgA testing recommended to identify IgA deficiency.)
• May aid in monitoring adherence to gluten-free diet in celiac disease confirmed patients.

Mnemonic
EMA IGG
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Tue
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Contaminated specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Effective November 14, 2011

Less than 1:10
Interpretive Data
The presence of endomysial antibodies IgG, may be useful in identifying IgA-deficient patients at risk for celiac disease. To establish the diagnosis of celiac disease, a positive result must be confirmed through a biopsy of the small intestine.

Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
CPT Code(s)
86256
Components
Component Test Code*Component Chart NameLOINC
2005502Endomysial Antibody, IgG51699-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Anti-Endomysial Antibodies
  • EMA
  • EMA IgG
  • Gluten-Sensitive Enteropathy Tests
  • IgA Deficient Celiac Disease