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Methotrexate, Sensitive
2005405
Ordering Recommendation

Monitor methotrexate concentration.

Mnemonic
METREXSN
Methodology
Quantitative Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain red. Also acceptable: Green (sodium heparin), lavender (EDTA), pink (K2EDTA), or gray (sodium fluoride/potassium oxalate) 
Specimen Preparation
Protect from light during collection, storage, and shipment. Separate serum from cells within 2 hours of collection. Transfer 3 mL serum to an ARUP Amber Transport Tube. (Min: 1 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Serum separator tubes. Specimens not protected from light. 
Remarks
 
Stability
After separation from cells: Ambient: 4 hours; Refrigerated: 24 hours; Frozen: 6 months 
Reference Interval
Effective August 15, 2011
Therapeutic Range
Low dose0.50-1.00 µmol/L
High dose/24 hours5.00 µmol/L or less
48 hours0.50 µmol/L or less
72 hours0.10 µmol/L or less

Interpretive Data


Note
CPT Code(s)
80299
Components
Component Test Code*Component Chart NameLOINC
2005406Methotrexate, Sensitive14836-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • methotrexate drug level
  • methtrexate concentration
  • MTX