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Ganglioside (GM1, GD1b, and GQ1b) Antibodies, IgG and IgM
2004998
Ordering Recommendation

May have diagnostic relevance in multifocal motor neuropathy (MMN), Guillain-Barré syndrome (GBS), and Miller Fisher syndrome (MFS). For a more comprehensive ganglioside antibody panel when evaluating patients with autoimmune neuropathies, refer to 0051033. Test by itself is not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.

Mnemonic
GM1 LIGHT
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Fri
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Transfer 0.3 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
CSF, plasma, or other body fluids. Room temperature specimens. Contaminated, heat-inactivated, hemolyzed, severely icteric, or lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
Test Number
Components
Reference Interval
0050591Ganglioside (GM1) Antibodies, IgG and IgM
Test Number
Components
Reference Interval
 GM1 Antibody, IgGRefer to report
 GM1 Antibody, IgMRefer to report

 GD1b Antibody, IgM
29 IV or lessNegative
30-50 IVEquivocal
51-100 IVPositive
101 IV or greaterStrong positive

 GD1b Antibody, IgG
29 IV or lessNegative
30-50 IVEquivocal
51-100 IVPositive
101 IV or greaterStrong positive

 GQ1b Antibody, IgG
29 IV or lessNegative
30-50 IVEquivocal
51-100 IVPositive
101 IV or greaterStrong positive

 GQ1b Antibody, IgM
29 IV or lessNegative
30-50 IVEquivocal
51-100 IVPositive
101 IV or greaterStrong positive


Interpretive Data
Refer to report.

Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
CPT Code(s)
83516 x6
Components
Component Test Code*Component Chart NameLOINC
0050582GM1 Antibody, IgG51729-2
0050584GM1 Antibody, IgM51703-7
2004999GD1b Antibody, IgG56541-6
2005000GD1b Antibody, IgM58977-0
2005001GQ1b Antibody, IgG57660-3
2005002GQ1b Antibody, IgM56545-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Anti-GM Antibodies
  • Ganglioside Antibodies
  • Ganglioside (GM1) Antibodies, IgG and IgM
  • Ganglioside Abs IgG and IgM
  • GD1b IgG IgM
  • GM1, GD1b, GQ1b IgG and IgM
  • GQ1b IgG IgM