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BCR-ABL1, T315I Mutation Detection, Quantitative (INACTIVE as of 2/18/14. Refer to 2008420)
2004924
Ordering Recommendation
Mnemonic
ABL T315I
Methodology
Reverse Transcription Polymerase Chain Reaction/Pyrosequencing
Performed
RNA isolation: Sun-Sat
Assay: Varies
Reported
10-12 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or bone marrow (EDTA). 
Specimen Preparation
Transport 5 mL whole blood or 3 mL bone marrow. (Min: 1 mL whole blood or 1 mL bone marrow) Specimens must be received within 48 hours of collection due to lability of RNA. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Serum or plasma. Specimens collected in anticoagulants other than EDTA. Frozen specimens. Clotted or severely hemolyzed specimens. 
Remarks
 
Stability
Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable 
Reference Interval
Interpretive Data
Refer to report.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
This test will only detect the BCR-ABL1 T315I mutation. For a more comprehensive ABL1 mutation detection test, please order BCR-ABL1 Mutation Analysis (ARUP test code 2008420).
CPT Code(s)
81401
Components
Component Test Code*Component Chart NameLOINC
2004925BCR-ABL1, T315I Mutation, Results
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • BCR/ABL1 T3151
  • TKI resistance testing