Confirm diagnosis of NMDAR antibody encephalitis.
Semi-Quantitative Indirect Fluorescent Antibody
This test is New York DOH approved.
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Effective May 21, 2012
Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.
If NMDA antibody IgG is positive, then an NMDA antibody IgG titer is reported. Additional charges apply.
86255; if reflexed, add 86256
|Component Test Code*||Component Chart Name|
|2004222||N-methyl-D-Aspartate Receptor Ab, Serum|
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at firstname.lastname@example.org.
- Glutamate Receptor Antibodies (N-methyl-D-Aspartate Receptor Antibody, IgG, Serum)
- NMDA R (N-methyl-D-Aspartate Receptor Antibody, IgG, Serum)