S-100 Protein by Immunohistochemistry
Immunohistochemistry Stain Form Recommended  (ARUP form #32978)Immunohistochemistry Stain Form Recommended (ARUP form #32978)

Ordering Recommendation
Submit With Order
S100 IHC
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Tissue or cells.  
Specimen Preparation
Formalin fix (10% neutral buffered formalin is preferred) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin from excessive heat. Transport tissue block or 5 unstained (3-5 micron thick sections), on positively charged slides (Min: 2 slides). If sending precut slides, do not oven bake.  
Storage/Transport Temperature
Room temperature or refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Specimens submitted with non-representative tissue type. Depleted specimens.  
IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (form #32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services.  
Ambient: Indefinite, Refrigerated: Indefinite, Frozen: Unacceptable  
Reference Interval
Interpretive Data
All stains will be handled as "Stain and Return" unless a consultation is requested. To request a consultation, submit the pathology report, all associated case materials (clinical history, blocks, slides, etc.), and the Anatomic Pathology requisition form (form # 32960).
CPT Code(s)
Component Test Code*Component Chart Name
2004128S100 Protein by IHC
2004129S100 Protein Reference Number
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • S-100 IHC
  • S-100 Immunostaining