Bleeding Disorders (Common)
2003417
 
Ordering Recommendation
Recommended panel in initial workup of suspected bleeding disorder. Appropriate initial workup should be guided by results of coagulation screening tests.
Mnemonic
BLEED COM
Methodology
Microlatex Particle-Mediated Immunoassay/Platelet Agglutination/Electromagnetic Mechanical Clot Detection
Performed
Sun-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 4 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 2 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum. Non-frozen or hemolyzed specimens.  
Remarks
 
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months  
Reference Interval
Available Separately Components Reference Interval
0030215Prothrombin Time 12.0-​15.5 seconds
0030235Partial Thromboplastin Time 24-​35 seconds
0030095Factor VIII, Activity 0-​6 years: 56-​191%
7-​9 years: 76-​199%
10-​11 years: 80-​209%
12-​13 years: 72-​198%
14-​15 years: 69-​237%
16-​17 years: 63-​221%
18 years and older: 56-​191%
0030285von Willebrand Factor Antigen 0-​6 years: 52-​214%
7-​9 years: 62-​180%
10-​11 years: 63-​189%
12-​13 years: 60-​189%
14-​15 years: 57-​199%
16-​17 years: 50-​205%
18 years and older: 52-​214%
0030250von Willebrand Factor Activity (Ristocetin Cofactor) 0-​6 years: 51-​215%
7-​9 years: 52-​176%
10-​11 years: 60-​195%
12-​13 years: 50-​184%
14-​15 years: 50-​203 %
16-​17 years: 49-​204%
18 years and older: 51-​215%
0030100Factor IX, Activity 1-​4 days: 15-​91%
5-​29 days: 15-​91%
30-​89 days: 21-​81%
90-​179 days: 21-​113%
180-​364 days: 36-​136%
1-​5 years: 47-​104%
6 years: 63-​89%
7-​9 years: 70-​133%
10-​11 years: 72-​149%
12-​13 years: 73-​152%
14-​15 years: 80-​161%
16-​17 years: 86-​176%
18 years and older: 78-​184%
0030110Factor XI, Activity 1-​4 days: 10-​66%
5-​29 days: 23-​87%
30-​89 days: 27-​79%
90-​179 days: 41-​97%
180-​364 days: 38-​134%
1-​5 years: 56-​150%
6 years: 52-​120%
7-​9 years: 70-​138%
10-​11 years: 66-​137%
12-​13 years: 68-​138%
14-​15 years: 57-​129%
16-​17 years: 65-​159%
18 years and older: 56-​153%
Interpretive Data
Note
CPT Code(s)
85240; 85246; 85245; 85250; 85270; 85610; 85730
Components
Component Test Code*Component Chart Name
0030095Factor VIII, Activity
0030100Factor IX, Activity
0030110Factor XI, Activity
0030220Prothrombin Time
0030235Partial Thromboplastin Time
0030250von Willebrand Factor, Activity (RCF)
0030285von Willebrand Factor, Antigen
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • F11
  • F8 Activity, Factor VIII, Activity
  • F9
  • Factor IX Activity
  • Factor XI Activity
  • Partial thromboplastin time
  • Prothrombin Time
  • PT
  • PTT
  • von Willebrand Factor Activity (RCF)
  • von Willebrand Factor, Antigen
  • vWF Ag
  • vWF RCF