von Willebrand Panel with Reflex to von Willebrand Multimeric Analysis
2003387
 
Ordering Recommendation
Recommended reflex panel to diagnose and subclassify suspected von Willebrand disease.
Mnemonic
VW PANEL R
Methodology
Electrophoresis/Western Blot/Clotting/Microlatex Particle-Mediated Immunoassay/Platelet Agglutination
Performed
Mon-Sat
Reported
1-11 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 3 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum. Non-frozen or hemolyzed specimens.  
Remarks
 
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months  
Reference Interval
Available Separately Components Reference Interval
0092281von Willebrand Factor Multimers By report
0030095Factor VIII, Activity 0-​6 years: 56-​191%
7-​9 years: 76-​199%
10-​11 years: 80-​209%
12-​13 years: 72-​198%
14-​15 years: 69-​237%
16-​17 years: 63-​221%
18 years and older: 56-​191%
0030285von Willebrand Factor Antigen 0-​6 years: 52-​214%
7-​9 years: 62-​180%
10-​11 years: 63-​189%
12-​13 years: 60-​189%
14-​15 years: 57-​199%
16-​17 years: 50-​205%
18 years and older: 52-​214%
0030250von Willebrand Factor Activity (Ristocetin Cofactor) 0-​6 years: 51-​215%
7-​9 years: 52-​176%
10-​11 years: 60-​195%
12-​13 years: 50-​184%
14-​15 years: 50-​203 %
16-​17 years: 49-​204%
18 years and older: 51-​215%
Interpretive Data
Note
If von Willebrand ristocetin cofactor (RCF) or von Willebrand factor antigen (vWF Ag) or Factor VIII is low, von Willebrand Multimeric Analysis testing will be added. If the ratio of RCF/vWF Ag is less than 0.7, vW Multimeric Analysis testing will be added.
CPT Code(s)
85240 F8; 85246 vWF/AG; 85245 RCF; If reflexed add 85247 vW Multi
Components
Component Test Code*Component Chart Name
0030095Factor VIII, Activity
0030250von Willebrand Factor, Activity (RCF)
0030285von Willebrand Factor, Antigen
2003388von Willebrand Factor, RCF/Ag Ratio
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Coag
  • von Willebrand Profile