Preferred panel for the workup of suspected rheumatoid arthritis or undifferentiated inflammatory arthritides.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Immunoturbidimetry
This test is New York DOH approved.
Anti-cyclic citrullinated peptide (anti-CCP) IgG antibodies are present in about 69-83 percent of patients with rheumatoid arthritis (RA) and have specificities of 93-95 percent. These autoantibodies may be present in the preclinical phase of disease, are associated with future RA development, and may predict radiographic joint destruction. Patients with weak positive results should be monitored and testing repeated.