Enterovirus Antibody Panel (INACTIVE as of 02/21/17: Refer to 2014108 in the February Hotline)
Ordering Recommendation
Serum Neutralization/Complement Fixation
6-9 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube. 
Specimen Preparation
Separate serum from cells within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.75 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent." 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, hemolyzed, or severely lipemic specimens. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Reference Interval
0050503Coxsackie A9 Virus Antibodies by CF< 1:8
0060055Coxsackie B Virus AntibodiesCoxsackie B1: Less than 1:10
Coxsackie B2: Less than 1:10
Coxsackie B3: Less than 1:10
Coxsackie B4: Less than 1:10
Coxsackie B5: Less than 1:10
Coxsackie B6: Less than 1:10
0060053Echovirus AntibodiesEchovirus 6:  Less than 1:10
Echovirus 7:  Less than 1:10
Echovirus 9:  Less than 1:10
Echovirus 11: Less than 1:10
Echovirus 30: Less than 1:10
0060054Poliovirus Antibodies (INACTIVE as of 02/21/17: Refer to 2014107 in the February Hotline)Less than 1:10:  No detectable poliovirus antibodies.
1:10 or greater: Antibody to poliovirus detected, which may represent prior immunization or current or past infection.

Interpretive Data
The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against other types.

Reference Interval applies to Poliovirus Antibody Types 1, 2 and 3.

CPT Code(s)
86658 x15
Component Test Code*Component Chart NameLOINC
0050503Coxsackie A Serotype 9 Titer9757-6
0065111Coxsackie B Virus Antibody Type 15103-7
0065112Coxsackie B Virus Antibody Type 25105-2
0065113Coxsackie B Virus Antibody Type 35107-8
0065114Echovirus Antibody Type 65144-1
0065116Echovirus Antibody Type 741492-0
0065117Echovirus Antibody Type 1141489-6
0065119Echovirus Antibody Type 3041491-2
0065123Coxsackie B Virus Antibody Type 55111-0
0065124Coxsackie B Virus Antibody Type 65113-6
0065126Polio Virus Antibody Type 15281-1
0065127Polio Virus Antibody Type 25283-7
0065128Polio Virus Antibody Type 35285-2
0065130Coxsackie B Virus Antibody Type 45109-4
0065132Echovirus Antibody Type 95146-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Coxsackie A
  • Coxsackie B
  • Echovirus
  • Ent Pan
  • Enterovirus Antibodies Profile
  • Enterovirus Panel
  • non-polio enterovirus testing
  • Poliovirus