Cortisol by LC-MS/MS, Serum or Plasma
2003250
 
Ordering Recommendation
Mnemonic
CORT TMS
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
It is recommended that the specimen be collected between 6-11 a.m.  
Collect
Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.5 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Room temperature specimens.  
Remarks
 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months  
Reference Interval
Adult Reference Ranges for Cortisol, Serum, µg/dL
AM 4.6-​20.6 µg/dL
PM 1.8-​13.6 µg/dL
Stimulation 30-​60 Minutes Post 0.25 mg Cosyntropin IV Greater than 20.0 µg/dL

Pediatric Reference Ranges for Cortisol, Serum, µg/dL
AM
1-​12 months 4.6-​23.0 µg/dL
1-​5 years 6.0-​25.0 µg/dL
6-​17 years 4.6-​15.0 µg/dL
Stimulation 30-​60 Minutes Post 0.25 mg Cosyntropin IV
1-​12 months 32.0-​60.0 µg/dL
1-​5 years 22.0-​40.0 µg/dL
6-​17 years 17.0-​28.0 µg/dL
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Note
CPT Code(s)
82533
Components
Component Test Code*Component Chart Name
2003251Cortisol by LC-MS/MS, Serum or Plasma
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References