Cortisol by LC-MS/MS, Serum or Plasma
2003250
Ordering Recommendation
 
Mnemonic
CORT TMS
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun
Reported
1-8 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
It is recommended that the specimen be collected between 6-11 a.m.  
Collect
Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.5 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Room temperature specimens.  
Remarks
  
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months  
Reference Interval
 
 
Adult Reference Ranges for Cortisol, Serum, µg/dL
AM 4.6-​20.6 µg/dL
PM 1.8-​13.6 µg/dL
Stimulation 30-​60  Minutes Post 0.25 mg Cosyntropin IV Greater than 20.0 µg/dL

 
Pediatric Reference Ranges for Cortisol, Serum, µg/dL
AM  
1-​12 months 4.6-​23.0 µg/dL
1-​5 years 6.0-​25.0 µg/dL
6-​17 years 4.6-​15.0 µg/dL
Stimulation 30-​60 Minutes Post 0.25 mg Cosyntropin IV  
1-​12 months 32.0-​60.0 µg/dL
1-​5 years 22.0-​40.0 µg/dL
6-​17 years 17.0-​28.0 µg/dL
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
82533
Components
Component Test Code*Component Chart NameLOINC
2003251Cortisol by LC-MS/MS, Serum or Plasma 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases