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Dexamethasone, Serum or Plasma by LC-MS/MS
2003248
Ordering Recommendation

Compliance assessment of dexamethasone suppression testing.

Mnemonic
DEXA TMS
Methodology
Liquid Chromatography-Tandem Mass Spectrometry
Performed
Wed, Sat
Reported
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Specimen should be collected between 8-10 a.m.  
Collect
Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
 
Remarks
 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months  
Reference Interval
Adults baseline: Less than 50 ng/dL
8:00 AM draw following 1 mg dexamethasone between 11:00 pm and 12:00 am the previous evening: 140 - 295 ng/dL
8:00 AM draw following 8 mg dexamethasone (4 x 2 mg doses) between 11:00 pm and 12:00 am the previous evening: 1600 - 2850 ng/dL
Interpretive Data


Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Note
CPT Code(s)
80299
Components
Component Test Code*Component Chart NameLOINC
2003249Dexamethasone, Serum or Plasma, LC-MS/MS14062-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases