Lacosamide, Serum or Plasma
2003182
Ordering Recommendation
Therapeutic drug monitoring.
Submit With Order
Mnemonic
LACOSA SP
Methodology
High Performance Liquid Chromatography/Tandem Mass Spectrometry
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.  
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).  
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated: Also acceptable: Room temperature or frozen.  
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).  
Remarks
 
Stability
Ambient: 15 days; Refrigerated: 15 days; Frozen: 15 days  
Reference Interval
Effective February 19, 2013
Reference Interval:
Therapeutic Range: Not well established. Suggested range 5.0-​10.0 µg/mL
Dose-​related range (values at doses of 200-​600 mg/day): 2.5-​18.0 µg/mL
Toxic Level Not well established.
Interpretive Data
Adverse effects may include dizziness, fatigue, nausea, vomiting, blurred vision and tremor.

See Compliance Statement B: www.aruplab.com/CS
Note
CPT Code(s)
80299
Components
Component Test Code*Component Chart Name
2003183Lacosamide, Serum or Plasma
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Lacosaminde blood level
  • Vimpat
  • vimpat blood level