Quetiapine, Serum or Plasma
Ordering Recommendation
Optimize drug therapy and monitor patient adherence.
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Tue, Fri
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).  
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).  
Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month  
Reference Interval
Interpretive Data
The following therapeutic ranges and toxic values have been suggested but have not been validated.
Adverse effects may include somnolence, dizziness, fatigue, constipation, weight gain.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Predose Draw (Trough) -​ Preferred
Therapeutic range 70-​170 ng/mL
Toxic: Greater than 1000 ng/mL

Peak Draw (1.5 hour post dose) -​ Not recommended
Therapeutic range 100-​1000 ng/mL
Toxic: Greater than 1500  ng/mL
CPT Code(s)
80342; (Alt code: 80299)
Component Test Code*Component Chart NameLOINC
2003119Quetiapine, Serum/Plasma26776-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • (Seroquel
  • quetiapine blood level
  • seroquel
  • seroquel blood level