Human Papillomavirus (HPV) Low Risk by in situ Hybridization, Paraffin
2002896
Ordering Recommendation
Not recommended for clinical use. Preferred test is HPV high-risk in situ hybridization.
Mnemonic
HPVLOW ISH
Methodology
In situ Hybridization
Performed
Mon-Thu
Reported
2-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Tissue.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Transport tissue block or 5 unstained positively charged, 5-micron slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 3 slides) Protect paraffin block and/or slides from excessive heat.  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). Frozen specimens.  
Remarks
Include surgical pathology report.  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
This test detects genotypes: 6,11.

A negative result does not rule out the presence of an HPV genotype absent from the test panel, a low level infection, or specimen sampling error.

See Compliance Statement A: www.aruplab.com/CS
Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.
 
Note
 
CPT Code(s)
88365
Components
Component Test Code*Component Chart Name
2002895HPV Low Risk ISH Comment
2002999ISH Tissue Source
2003000ISH Reference Number
2003001H and E Slide Description
2003008HPV ISH Low Risk
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • HPV
  • HPV Low Risk ISH
  • HPV LR ISH
  • HPVLOW ISH
  • Human Papillomavirus
  • low-risk HPV ISH
  • LR-HPV ISH