Buprenorphine and Metabolites - Confirmation/Quantitation - Urine
2002749
Ordering Recommendation
 
Mnemonic
BUPREN UR
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Random urine.  
Specimen Preparation
Transfer 2 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Specimens exposed to repeated freeze/thaw cycles.  
Remarks
  
Stability
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years  
Reference Interval
   
Interpretive Data
Methodology:Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Drugs covered:
Buprenorphine, norbuprenorphine, buprenorphine glucuronide (qualitative only), norbuprenorphine glucuronide (qualitative only), and naloxone.

Positive cutoff:

Buprenorphine: 2 ng/mL
Norbuprenorphine: 2 ng/mL
Buprenorphine glucuronide: 5 ng/mL
Norbuprenorphine glucuronide: 5 ng/mL
Naloxone 100 ng/mL

For medical purposes only; not valid for forensic use.

The presence of metabolite(s) without parent drug is common and may indicate use of parent drug during the prior week.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

See Compliance Statement B: www.aruplab.com/CS  
Note
 
CPT Code(s)
83925
Components
Component Test Code*Component Chart Name
2002750Norbuprenorphine, Urine
2002751Buprenorphine Glucuronide, Urine
2002752Buprenorphine, Urine
2002753Norbuprenorphine Glucuronide, Urine
2005863Naloxone, Urine
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Buprenex (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Buprenorphine (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Buprenorphine Glucuronide (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Buprenorphine Screen & Metabolite (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Butrans (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Norbuprenorphine (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Norbuprenorphine Glucuronide (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Norspan (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Pain Management (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Pain Management, Buprenorphine, Quantitative, w/ medMATCH, Urine (Buprenorphine & Metabolites-Confirmation/Quantitation-Urine)
  • Pain Management, Buprenorphine, w/ Confirmation w/ medMATCH, Urine (Buprenorphine & Metabolites-Confirmation/Quantitation-Urine)
  • Suboxone (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Subutex (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Temgesic (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Transtec (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)
  • Vetergesic (Buprenorphine & Metabolites - Confirmation/Quantitation - Urine)