Myelodysplastic Syndrome (MDS) Panel by FISH
Ordering Recommendation
Use in conjunction with conventional cytogenetics for diagnosis, prognosis, and monitoring of minimal residual disease (MRD) in MDS.
Fluorescence in situ Hybridization
On request
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Non-diluted bone marrow collected in a heparinized syringe. Also acceptable: Green (sodium heparin).
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.  
Specimen Preparation
Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL). OR transport 5 mL whole blood (Min: 2 mL).  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Frozen specimens. Paraffin-embedded specimens. Clotted specimens.  
If cell pellets or dropped cytogenetics slides are submitted, a processing fee will not apply. This test must be ordered using Oncology test request form (#43099) or through your ARUP interface.  
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
Probes included: EGR1 (5q del), D7S486 (7q del/-7), CEP8 (+8), D20S108 (20q del)

See Compliance Statement A:
A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type. To order probes separately, refer to Chromosome FISH, Interphase (2002298).
CPT Code(s)
88271 x4; 88275 x4; 88291
Component Test Code*Component Chart Name
2002710MDS Panel by FISH
2002711EER MDS Panel by FISH
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at
Cross References