Cryoglobulin, Qualitative with Reflex to IFE Typing and Quantitative IgA, IgG, and IgM
Ordering Recommendation
Qualitative Cold Precipitation/Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry
3-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Fasting specimen required.  
Whole blood drawn in a pre-warmed (37°C) syringe. Specimen may be drawn directly into a pre-warmed plain red.  
Specimen Preparation
Maintain whole blood at 37°C until clotting is complete; do not refrigerate or freeze at any time. Immediately after blood has been obtained, transfer specimen to a pre-warmed plain red (if not used for collection). Separate serum from cells using a 37°C centrifuge, if possible. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 3 mL)  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated.  
Unacceptable Conditions
Plasma. Serum separator tubes. Grossly hemolyzed or lipemic specimens.  
Proper collection and transport of specimen is critical to the outcome of the test. Quantities less than 3 mL may affect the sensitivity of the test.  
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable  
Reference Interval
Available Separately Components Reference Interval
0050185Cryoglobulin, Qualitative Negative at 72 hours.
0050272Immunofixation Electrophoresis Gel Normal IFE
 Immunoglobulin A, Cryoprecipitate 0 mg/dL
 Immunoglobulin G, Cryoprecipitate 0 mg/dL
 Immunoglobulin M, Cryoprecipitate 0 mg/dL
Interpretive Data

See Compliance Statement B:  
If Cryoglobulin Qualitative is positive, then Immunofixation Electrophoresis Typing and Quantitative IgA, IgG and IgM will be added. Additional charges apply.
CPT Code(s)
82595; if reflexed, add 86334 and 82784 x3
Component Test Code*Component Chart Name
0050185Cryoglobulin, Qualitative
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Cryocrit
  • Cryoglobulins reflex test to IFE
  • Cryoglobulins/cryoglobulins
  • Cryoprotein
  • Quantitative cryoglobulins