Cytogenomic SNP Microarray - Fetal
2002366
Time SensitiveTime Sensitive

Additional Technical InformationAdditional Technical Information

Cytogenetic Test Request Form Recommended (ARUP form #43097)Cytogenetic Test Request Form Recommended (ARUP form #43097)

Ordering Recommendation
Indications for use
• Clarify abnormal ultrasound findings
• Further characterize an abnormal fetal karyotype
• Suspicion of an imbalance in a specific genomic region that is best evaluated by microarray
• Investigate de novo, apparently balanced translocations
• Family history of a known or suspected chromosomal abnormality best evaluated by microarray
• Patients undergoing invasive prenatal testing (instead of, or in addition to, chromosome analysis)
Mnemonic
ARRAY FE
Methodology
Genomic Microarray (Oligo-SNP Array)
Performed
Sat-Sun
Reported
Varies
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
 
Collect
Fetal Specimen: Amniotic fluid OR chorionic villi in cytogenetic tissue media (ARUP Supply #32788). If cytogenetic tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers.  
Specimen Preparation
Do not freeze specimen or expose to extreme temperatures. Do not place in formalin.
Transport 35-45 mL amniotic fluid in a sterile container (Min: 10 mL) OR 20-30 mg CVS in a sterile, screw-top container filled with tissue culture transport medium. (Min: 5 mg)  
Storage/Transport Temperature
Room temperature (all specimens).  
Unacceptable Conditions
Frozen or fixed specimens.  
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: Acceptable but not ideal; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
This test must be ordered using Cytogenetic test request form 43097 or through your ARUP interface. Please submit the Cytogenetics and Chromosome Studies Information Form with the electronic packing list.



Counseling and informed consent are recommended for genetic testing. Consent forms are available online at www.aruplab.com.

See Compliance Statement C: www.aruplab.com/CS
Note
Maternal Cell Contamination: Maternal cell contamination studies recommended. For Array AND amniotic fluid chromosomes, also order Chromosome Analysis, Amniotic fluid (ARUP test code 2002293). For Array AND CVS chromosomes, also order Chromosome Analysis, Chorionic Villus (ARUP test code 2002291). For maternal cell contamination studies or if submitting maternal blood, order Microarray Genomic, Maternal Confirm (ARUP test code 2002369) accompanied by a test request form for the mother (this test is performed at no charge). For questions regarding ordering please contact ARUP's genetic counselor at (800) 242-2787 ext. 2141.

A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type.
CPT Code(s)
81229
Components
Component Test Code*Component Chart Name
0050548Maternal Cell Contamination, Fetal Spec
2002367EER Cytogenomic SNP Microarray - Fetal
2002368Cytogenomic SNP Microarray - Fetal
2002523Maternal Specimen
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Array CGH
  • Comparative Genomic Hybridization
  • Microarray Genomic, Fetal
  • Oligo Array