Cytogenomic SNP Microarray - Fetal
Ordering Recommendation
Indications for use
• Clarify abnormal ultrasound findings
• Further characterize an abnormal fetal karyotype
• Suspicion of an imbalance in a specific genomic region that is best evaluated by microarray
• Investigate de novo, apparently balanced translocations
• Family history of a known or suspected chromosomal abnormality best evaluated by microarray
• Patients undergoing invasive prenatal testing (instead of, or in addition to, chromosome analysis)
Genomic Microarray (Oligo-SNP Array)
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Time SensitiveTime Sensitive

Additional Technical InformationAdditional Technical Information

Cytogenetic Test Request Form Recommended (ARUP form #43097)Cytogenetic Test Request Form Recommended (ARUP form #43097)

Specimen Required
Patient Preparation
Fetal Specimen: Amniotic fluid OR chorionic villi in cytogenetic tissue media (ARUP Supply #32788). If cytogenetic tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers.  
Specimen Preparation
Do not freeze specimen or expose to extreme temperatures. Do not place in formalin.
Transport 35-45 mL amniotic fluid in a sterile container (Min: 10 mL) OR 20-30 mg CVS in a sterile, screw-top container filled with tissue culture transport medium. (Min: 5 mg)  
Storage/Transport Temperature
Room temperature (all specimens).  
Unacceptable Conditions
Frozen or fixed specimens.  
Ambient: 48 hours; Refrigerated: Acceptable but not ideal; Frozen: Unacceptable  
Reference Interval
By report  
Interpretive Data
This test must be ordered using Cytogenetic test request form 43097 or through your ARUP interface. Please submit the Cytogenetics and Chromosome Studies Information Form with the electronic packing list.

See Compliance Statement C:
Statement C: The performance characteristics of this test were validated by ARUP Laboratories. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test; however, FDA approval or clearance is currently not required for clinical use of this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. ARUP is authorized under Clinical Laboratory Improvement Amendments (CLIA) and by all states to perform high-complexity testing.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Maternal Cell Contamination: Maternal cell contamination studies recommended. For Array AND amniotic fluid chromosomes, also order Chromosome Analysis, Amniotic fluid (ARUP test code 2002293). For Array AND CVS chromosomes, also order Chromosome Analysis, Chorionic Villus (ARUP test code 2002291). For maternal cell contamination studies or if submitting maternal blood, order Microarray Genomic, Maternal Confirm (ARUP test code 2002369) accompanied by a test request form for the mother (this test is performed at no charge). For questions regarding ordering please contact ARUP's genetic counselor at (800) 242-2787 ext. 2141.

A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type.
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0050548Maternal Cell Contamination, Fetal Spec31208-2
2002367EER Cytogenomic SNP Microarray - Fetal11526-1
2002368Cytogenomic SNP Microarray - Fetal62356-1
2002523Maternal Specimen8251-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Array CGH
  • Comparative Genomic Hybridization
  • Microarray Genomic, Fetal
  • Oligo Array