Chromosome FISH, CLL Panel
Additional Technical InformationAdditional Technical Information

Oncology Test Request Form Recommended (ARUP form #43099)Oncology Test Request Form Recommended (ARUP form #43099)

Ordering Recommendation
Alternate test to detect prognostically important genomic abnormalities in CLL.
Submit With Order
Fluorescence in situ Hybridization
3-10 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Green (sodium heparin). Also acceptable: Non-diluted bone marrow aspirate collected in a heparinized syringe.  
Specimen Preparation
Transport 5 mL whole blood (Min: 2 mL). OR Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL)  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Frozen specimens. Paraffin-embedded specimens. Clotted specimens.  
Ambient: 48 hours; Refrigerated: 48 hours; Frozen; Unacceptable.  
Reference Interval
By report
Interpretive Data

See Compliance Statement A:
Fluorescence in situ Hybridization panel is performed for CLL prognosis-specific genomic abnormalities as follows: ATM deletion, D13S319 deletion, Trisomy 12, TP53 deletion.

A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth

If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.

This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
CPT Code(s)
88271 x4; 88275 x4; 88291
Component Test Code*Component Chart Name
0092616Chromosome FISH, CLL Panel
2002197EER Chromosome FISH, CLL Panel
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • 'Chronic Lymphocytic Leukemia FISH Panel