Chromosome Analysis, Amniotic Fluid
Ordering Recommendation
Prenatal chromosome analysis after 14 weeks gestation.
Giemsa Band
7-14 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Amniotic fluid.  
Specimen Preparation
Do not freeze or expose to extreme temperatures. Transport 30 mL amniotic fluid in a sterile container. (Min: 15 mL) Specimen and completed test request form, including clinical indication, must be received within 48 hours of collection.  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Frozen specimens. Bloody specimens.  
This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient History for Prenatal Cytogenetics form (available at  
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
Counseling and informed consent are recommended for genetic testing. Consent forms are available online at
These studies involve culturing of living cells; therefore, turnaround times given represent average times which are subject to multiple variables. Results are generally available in an average of 12 days after receipt of a specimen.

A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth.
CPT Code(s)
88269; 88235; 88291
Component Test Code*Component Chart Name
0097601Chromosome Analysis, Amniotic Fluid
2002199EER Chromosome Analysis Amniotic Fluid
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at
Cross References
  • Karyotype, Amniotic Fluid
  • NIPD confirmation study
  • NIPT confirmation study
  • Prenatal Diagnosis, Amniotic Fluid, Prenatal Chromosomes, Amniotic Fluid