Chromosome Analysis, Amniotic Fluid
Ordering Recommendation
Prenatal chromosome analysis on amniotic fluid when individual
Is at increased risk for fetal aneuploidy based on maternal age, abnormal NIPT, abnormal multiple marker screening, or abnormal fetal ultrasound.
Has a family history of chromosome abnormality or genetic disorder.
Desires diagnostic testing instead of screening.
Giemsa Band
7-14 days
New York DOH Approval Status
This test is New York DOH approved.
Time SensitiveTime Sensitive
Cytogenetic Test Request Form Recommended (ARUP form #43097)Cytogenetic Test Request Form Recommended (ARUP form #43097)
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Amniotic fluid.  
Specimen Preparation
Do not freeze or expose to extreme temperatures. Transport 30 mL amniotic fluid in a sterile container. (Min: 15 mL)  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Frozen specimens. Bloody specimens.  
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
Counseling and informed consent are recommended for genetic testing. Consent forms are available online at

These studies involve culturing of living cells; therefore, turnaround times given represent average times which are subject to multiple variables. Results are generally available in an average of 12 days after receipt of a specimen.

A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth.

Specimen and completed test request form, including clinical indication, must be received within 48 hours of collection.

This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient History for Prenatal Cytogenetics form (available at
CPT Code(s)
88269; 88235; 88291
Component Test Code*Component Chart NameLOINC
0097601Chromosome Analysis, Amniotic Fluid33773-3
2002199EER Chromosome Analysis Amniotic Fluid
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Karyotype, Amniotic Fluid
  • NIPD confirmation study
  • NIPT confirmation study
  • Prenatal Diagnosis, Amniotic Fluid, Prenatal Chromosomes, Amniotic Fluid