Congenital Adrenal Hyperplasia Panel, 11-Beta Hydroxylase Deficiency
2002282
Ordering Recommendation
 
Mnemonic
CAH 11-B HYDROX
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Collect between 6-10 a.m.  
Collect
Serum separator tube or green (sodium or lithium heparin). Also acceptable: Pink (K2EDTA).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1.2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.7 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
  
Remarks
  
Stability
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months  
Reference Interval
 
 
Test Number Components Reference Interval
2001638Androstenedione Effective August 19, 2013
 
Age Female Male
Premature Infants, 26-​28 weeks-​Day 4 0.92-​2.82 ng/mL 0.92-​2.82 ng/mL
Premature Infants, 31-​35 weeks-​Day 4 0.80-​4.46 ng/mL 0.80-​4.46 ng/mL
Full-​term Infants, 1-​7 days 0.20-​2.90 ng/mL 0.20-​2.90 ng/mL
8-​30 days 0.18-​0.80 ng/mL 0.18-​0.80 ng/mL
1-​5 months 0.06-​0.68 ng/mL 0.06-​0.68 ng/mL
6-​24 months Less than 0.15 ng/mL 0.03-​0.15 ng/mL
2-​3 years Less than 0.16 ng/mL Less than 0.11 ng/mL
4-​5 years 0.02-​0.21 ng/mL 0.02-​0.17 ng/mL
6-​7 years 0.02-​0.28 ng/mL 0.01-​0.29 ng/mL
8-​9 years 0.04-​0.42 ng/mL 0.03-​0.30 ng/mL
10-​11 years 0.09-​1.23 ng/mL 0.07-​0.39 ng/mL
12-​13 years 0.24-​1.73 ng/mL 0.10-​0.64 ng/mL
14-​15 years 0.39-​2.00 ng/mL 0.18-​0.94 ng/mL
16-​17 years 0.35-​2.12 ng/mL 0.30-​1.13 ng/mL
18-​39 years 0.26-​2.14 ng/mL 0.33-​1.34 ng/mL
40 years and older 0.13-​0.82 ng/mL 0.23-​0.89 ng/mL
Pre-​menopausal 0.26-​2.14 ng/mL Does Not Apply
Postmenopausal 0.13-​0.82 ng/mL Does Not Apply
Tanner Stage I 0.05-​0.51 ng/mL 0.04-​0.32 ng/mL
Tanner Stage II 0.15-​1.37 ng/mL 0.08-​0.48 ng/mL
Tanner Stage III 0.37-​2.24 ng/mL 0.14-​0.87 ng/mL
Tanner Stage IV-​V 0.35-​2.05 ng/mL 0.27-​1.07 ng/mL
009233217-​Hydroxyprogesterone Quantitative by HPLC-​MS/MS, Serum or Plasma Effective August 19, 2013
 
Age Female Male
Premature (26-​28 weeks) 124-​841 ng/dL 124-​841 ng/dL
Premature (29-​35 weeks) 26-​568 ng/dL 26-​568 ng/dL
Full term Day 3 7-​77 ng/dL 7-​77 ng/dL
4 days-​30 days 7-​106 ng/dL Less than 200 ng/dL
1 month-​2 months 13-​106 ng/dL Less than 200 ng/dL
3 months-​5 months 13-​106 ng/dL 3-​90 ng/dL
6  months-​1 year Less than or equal to 148 ng/dL Less than or equal to 148 ng/dL
2-​3 years Less than or equal to 256 ng/dL Less than or equal to 228 ng/dL
4-​6 years Less than or equal to 299 ng/dL Less than or equal to 208 ng/dL
7-​9 years Less than or equal to 71 ng/dL Less than or equal to 63 ng/dL
10-​12 years Less than or equal to 129 ng/dL Less than or equal to 79 ng/dL
13-​15 years 9-​208 ng/dL 9-​140 ng/dL
16-​17 years Less than or equal to 178 ng/dL 24-​192 ng/dL
18 years and older Less than 207 ng/dL Less than 139 ng/dL
Follicular 15-​70 ng/dL Does Not Apply
Luteal 35-​290 ng/dL Does Not Apply
Tanner Stage I Less than or equal to 74 ng/dL Less than or equal to 62 ng/dL
Tanner Stage II Less than or equal to 164 ng/dL Less than or equal to 104 ng/dL
Tanner Stage III 13-​209 ng/dL Less than or equal to 151 ng/dL
Tanner Stage IV-​V 7-​170 ng/dL 20-​173 ng/dL
0081058Testosterone, Females or Children Effective August 19, 2013
 
Age Female Male
Premature (26-​28 weeks) 5-​16 ng/dL 59-​125 ng/dL
Premature (31-​35 weeks) 5-​22 ng/dL 37-​198 ng/dL
Newborn 20-​64 ng/dL 75-​400 ng/dL
1-​5 months Less than 20 ng/dL 14-​363 ng/dL
6-​24 months Less than 9 ng/dL Less than 37 ng/dL
2-​3 years Less than 20 ng/dL Less than 15 ng/dL
4-​5 years Less than 30 ng/dL Less than 19 ng/dL
6-​7 years Less than 7 ng/dL Less than 13 ng/dL
8-​9 years 1-​11ng/dL 2-​8 ng/dL
10-​11 years 3-​32 ng/dL 2-​165 ng/dL
12-​13 years 6-​50 ng/dL 3-​619 ng/dL
14-​15 years 6-​52 ng/dL 31-​733 ng/dL
16-​17 years 9-​58 ng/dL 158-​826 ng/dL
18-​39 years 9-​55 ng/dL 300-​1080 ng/dL
40-​59 years 9-​55 ng/dL 300-​890 ng/dL
60 years and older 5-​32 ng/dL 300-​720 ng/dL
Premenopausal (Greater than 18 years) 9-​55 ng/dL Does Not Apply
Postmenopausal 5-​32 ng/dL Does Not Apply
Tanner Stage I 2-​17 ng/dL 2-​15 ng/dL
Tanner Stage II 5-​40 ng/dL 3-​303 ng/dL
Tanner Stage III 10-​63 ng/dL 10-​851 ng/dL
Tanner Stage IV-​V 11-​62 ng/dL 162-​847 ng/dL
009233111-​Deoxycortisol Quantitative by HPLC-​MS/MS, Serum or Plasma Effective August 19, 2013
 
Age Female Male
Premature (26-​28 weeks) 110-​1376 ng/dL 110-​1376 ng/dL
Premature (29-​36 weeks) 70-​455 ng/dL 70-​455 ng/dL
Full Term (1-​5 months) 10-​200 ng/dL 10-​200 ng/dL
6-​11 months 10-​276 ng/dL 10-​276 ng/dL
1-​3 years 7-​247 ng/dL 7-​202 ng/dL
4-​6 years 8-​291 ng/dL 8-​235 ng/dL
7-​9 years Less than or equal to 94 ng/dL Less than or equal to 120 ng/dL
10-​12 years Less than or equal to 123 ng/dL Less than or equal to 92 ng/dL
13-​15 years Less than or equal to 107 ng/dL Less than or equal to 95 ng/dL
16-​17 years Less than or equal to 47 ng/dL Less than or equal to 106 ng/dL
18 years and older Less than 33 ng/dL Less than 50 ng/dL
Tanner Stage I Less than or equal to 94 ng/dL Less than or equal to 105 ng/dL
Tanner Stage II Less than or equal to 136 ng/dL Less than or equal to 108 ng/dL
Tanner Stage III Less than or equal to 99 ng/dL Less than or equal to 111 ng/dL
Tanner Stage IV & V Less than or equal to 50 ng/dL Less than or equal to 83 ng/dL
After metyrapone stimulation Greater than 8000 ng/dL Greater than 8000 ng/dL
 
2001640Dehydroepiandrosterone, Serum or Plasma Effective August 19, 2013
 
Age Female Male
Premature Less than 40 ng/mL Less than 40 ng/mL
0-​1 day Less than 11 ng/mL Less than 11 ng/mL
2-​6 days Less than 8.7 ng/mL Less than 8.7 ng/mL
7 days-​1 month Less than 5.8 ng/mL Less than 5.8 ng/mL
1-​5 months Less than 2.9 ng/mL Less than 2.9 ng/mL
6-​24 months Less than 1.9 9 ng/mL Less than 2.5 ng/mL
2-​3 years Less than 0.85 ng/mL Less than 0.63 ng/mL
4-​5 years Less than 1.03 ng/mL Less than 0.95 ng/mL
6-​7 years Less than 1.79 ng/mL 0.06-​1.93 ng/mL
8-​9 years 0.14-​2.35 ng/mL 0.10-​2.08 ng/mL
10-​11 years 0.43-​3.78 ng/mL 0.32-​3.08 ng/mL
12-​13 years 0.89-​6.21 ng/mL 0.57-​4.10 ng/mL
14-​15 years 1.22-​7.01 ng/mL 0.93-​6.04 ng/mL
16-​17 years 1.42-​9.00 ng/mL 1.17-​6.52 ng/mL
18-​39 years 1.33-​7.78 ng/mL 1.33-​7.78 ng/mL
40 years and older 0.63-​4.70 ng/mL 0.63-​4.70 ng/mL
Postmenopausal 0.60-​5.73 ng/mL Does Not Apply
Tanner Stage I 0.14-​2.76 ng/mL 0.11-​2.37 ng/mL
Tanner Stage II 0.83-​4.87 ng/mL 0.37-​3.66 ng/mL
Tanner Stage III 1.08-​7.56 ng/mL 0.75-​5.24 ng/mL
Tanner Stage IV-​V 1.24-​7.88 ng/mL 1.22-​6.73 ng/mL
Interpretive Data
Total testosterone values may not reflect optimal concentrations in all individuals. Free or bioavailable testosterone measurements may provide supportive information.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
82157; 83498; 84403; 82634; 82626
Components
Component Test Code*Component Chart NameLOINC
0081058Testosterone, LC-MS/MS2986-8
009233111-Deoxycortisol, HPLC-MS/MS1657-6
009233217-Hydroxyprogesterone, HPLC-MS/MS1668-3
2001639Androstenedione by TMS1854-9
2001641Dehydroepiandrosterone by TMS2193-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases