Virilization Panel 2
2002281
 
Ordering Recommendation
Aids in the detection of nonclassical congenital adrenal hyperplasia in individuals presenting with hyperandrogenism.
Mnemonic
VIRIL PAN2
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect between 6-10 a.m.  
Collect
Serum separator tube or green (sodium or lithium heparin). Also acceptable: Pink (K2EDTA).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1.2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.7 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
 
Remarks
 
Stability
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months  
Reference Interval
Available Separately Components Reference Interval
2001638Androstenedione Effective August 19, 2013
Age Female Male
Premature Infants, 26-​28 weeks-​Day 4 0.92-​2.82 ng/mL 0.92-​2.82 ng/mL
Premature Infants, 31-​35 weeks-​Day 4 0.80-​4.46 ng/mL 0.80-​4.46 ng/mL
Full-​term Infants, 1-​7 days 0.20-​2.90 ng/mL 0.20-​2.90 ng/mL
8-​30 days 0.18-​0.80 ng/mL 0.18-​0.80 ng/mL
1-​5 months 0.06-​0.68 ng/mL 0.06-​0.68 ng/mL
6-​24 months Less than 0.15 ng/mL 0.03-​0.15 ng/mL
2-​3 years Less than 0.16 ng/mL Less than 0.11 ng/mL
4-​5 years 0.02-​0.21 ng/mL 0.02-​0.17 ng/mL
6-​7 years 0.02-​0.28 ng/mL 0.01-​0.29 ng/mL
8-​9 years 0.04-​0.42 ng/mL 0.03-​0.30 ng/mL
10-​11 years 0.09-​1.23 ng/mL 0.07-​0.39 ng/mL
12-​13 years 0.24-​1.73 ng/mL 0.10-​0.64 ng/mL
14-​15 years 0.39-​2.00 ng/mL 0.18-​0.94 ng/mL
16-​17 years 0.35-​2.12 ng/mL 0.30-​1.13 ng/mL
18-​39 years 0.26-​2.14 ng/mL 0.33-​1.34 ng/mL
40 years and older 0.13-​0.82 ng/mL 0.23-​0.89 ng/mL
Pre-​menopausal 0.26-​2.14 ng/mL Does Not Apply
Postmenopausal 0.13-​0.82 ng/mL Does Not Apply
Tanner Stage I 0.05-​0.51 ng/mL 0.04-​0.32 ng/mL
Tanner Stage II 0.15-​1.37 ng/mL 0.08-​0.48 ng/mL
Tanner Stage III 0.37-​2.24 ng/mL 0.14-​0.87 ng/mL
Tanner Stage IV-​V 0.35-​2.05 ng/mL 0.27-​1.07 ng/mL
009233217-​Hydroxyprogesterone Quantitative by HPLC-​MS/MS, Serum or Plasma Effective August 19, 2013
Age Female Male
Premature (26-​28 weeks) 124-​841 ng/dL 124-​841 ng/dL
Premature (29-​35 weeks) 26-​568 ng/dL 26-​568 ng/dL
Full term Day 3 7-​77 ng/dL 7-​77 ng/dL
4 days-​30 days 7-​106 ng/dL Less than 200 ng/dL
1 month-​2 months 13-​106 ng/dL Less than 200 ng/dL
3 months-​5 months 13-​106 ng/dL 3-​90 ng/dL
6 months-​1 year Less than or equal to 148 ng/dL Less than or equal to 148 ng/dL
2-​3 years Less than or equal to 256 ng/dL Less than or equal to 228 ng/dL
4-​6 years Less than or equal to 299 ng/dL Less than or equal to 208 ng/dL
7-​9 years Less than or equal to 71 ng/dL Less than or equal to 63 ng/dL
10-​12 years Less than or equal to 129 ng/dL Less than or equal to 79 ng/dL
13-​15 years 9-​208 ng/dL 9-​140 ng/dL
16-​17 years Less than or equal to 178 ng/dL 24-​192 ng/dL
18 years and older Less than 207 ng/dL Less than 139 ng/dL
Follicular 15-​70 ng/dL Does Not Apply
Luteal 35-​290 ng/dL Does Not Apply
Tanner Stage I Less than or equal to 74 ng/dL Less than or equal to 62 ng/dL
Tanner Stage II Less than or equal to 164 ng/dL Less than or equal to 104 ng/dL
Tanner Stage III 13-​209 ng/dL Less than or equal to 151 ng/dL
Tanner Stage IV-​V 7-​170 ng/dL 20-​173 ng/dL
0081058Testosterone, Females or Children Effective August 19, 2013
Age Female Male
Premature (26-​28 weeks) 5-​16 ng/dL 59-​125 ng/dL
Premature (31-​35 weeks) 5-​22 ng/dL 37-​198 ng/dL
Newborn 20-​64 ng/dL 75-​400 ng/dL
1-​5 months Less than 20 ng/dL 14-​363 ng/dL
6-​24 months Less than 9 ng/dL Less than 37 ng/dL
2-​3 years Less than 20 ng/dL Less than 15 ng/dL
4-​5 years Less than 30 ng/dL Less than 19 ng/dL
6-​7 years Less than 7 ng/dL Less than 13 ng/dL
8-​9 years 1-​11ng/dL 2-​8 ng/dL
10-​11 years 3-​32 ng/dL 2-​165 ng/dL
12-​13 years 6-​50 ng/dL 3-​619 ng/dL
14-​15 years 6-​52 ng/dL 31-​733 ng/dL
16-​17 years 9-​58 ng/dL 158-​826 ng/dL
18-​39 years 9-​55 ng/dL 300-​1080 ng/dL
40-​59 years 9-​55 ng/dL 300-​890 ng/dL
60 years and older 5-​32 ng/dL 300-​720 ng/dL
Premenopausal (Greater than 18 years) 9-​55 ng/dL Does Not Apply
Postmenopausal 5-​32 ng/dL Does Not Apply
Tanner Stage I 2-​17 ng/dL 2-​15 ng/dL
Tanner Stage II 5-​40 ng/dL 3-​303 ng/dL
Tanner Stage III 10-​63 ng/dL 10-​851 ng/dL
Tanner Stage IV-​V 11-​62 ng/dL 162-​847 ng/dL
2001640Dehydroepiandrosterone, Serum or Plasma Effective August 19, 2013
Age Female Male
Premature Less than 40 ng/mL Less than 40 ng/mL
0-​1 day Less than 11 ng/mL Less than 11 ng/mL
2-​6 days Less than 8.7 ng/mL Less than 8.7 ng/mL
7 days-​1 month Less than 5.8 ng/mL Less than 5.8 ng/mL
1-​5 months Less than 2.9 ng/mL Less than 2.9 ng/mL
6-​24 months Less than 1.9 9 ng/mL Less than 2.5 ng/mL
2-​3 years Less than 0.85 ng/mL Less than 0.63 ng/mL
4-​5 years Less than 1.03 ng/mL Less than 0.95 ng/mL
6-​7 years Less than 1.79 ng/mL 0.06-​1.93 ng/mL
8-​9 years 0.14-​2.35 ng/mL 0.10-​2.08 ng/mL
10-​11 years 0.43-​3.78 ng/mL 0.32-​3.08 ng/mL
12-​13 years 0.89-​6.21 ng/mL 0.57-​4.10 ng/mL
14-​15 years 1.22-​7.01 ng/mL 0.93-​6.04 ng/mL
16-​17 years 1.42-​9.00 ng/mL 1.17-​6.52 ng/mL
18-​39 years 1.33-​7.78 ng/mL 1.33-​7.78 ng/mL
40 years and older 0.63-​4.70 ng/mL 0.63-​4.70 ng/mL
Postmenopausal 0.60-​5.73 ng/mL Does Not Apply
Tanner Stage I 0.14-​2.76 ng/mL 0.11-​2.37 ng/mL
Tanner Stage II 0.83-​4.87 ng/mL 0.37-​3.66 ng/mL
Tanner Stage III 1.08-​7.56 ng/mL 0.75-​5.24 ng/mL
Tanner Stage IV-​V 1.24-​7.88 ng/mL 1.22-​6.73 ng/mL
Interpretive Data
Total testosterone values may not reflect optimal concentrations in all individuals. Free or bioavailable testosterone measurements may provide supportive information.

See Compliance Statement B: www.aruplab.com/CS
Note
CPT Code(s)
82157; 83498; 84403; 82626
Components
Component Test Code*Component Chart Name
0081058Testosterone, LC-MS/MS
009233217-Hydroxyprogesterone, HPLC-MS/MS
2001639Androstenedione by TMS
2001641Dehydroepiandrosterone by TMS
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • 17-Hydroxyprogesterone (Virilization Panel 2)
  • Androstenedione (Virilization Panel 2)
  • Dehydroepiandrosterone (Virilization Panel 2)
  • Testosterone (Virilization Panel 2)