Osmotic Fragility, Erythrocyte
2002257
 
Time SensitiveTime Sensitive
Ordering Recommendation
Mnemonic
OSM FRG
Methodology
Spectrophotometry
Performed
Mon-Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Green (sodium or lithium heparin) or Lavender (EDTA).  
Specimen Preparation
Transport 2 unfixed, air-dried, and unstained smears to accompany the collected blood (smears should be made from the blood submitted) (Min: 2 smears). AND 5 mL whole blood (Min: 1 mL). Specimens should be refrigerated within 30 minutes after collection..  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Grossly hemolyzed specimens.  
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: Unacceptable  
Reference Interval
Within normal curve limits. A graph will accompany laboratory report.
Interpretive Data
For patients with acute hemolysis, a normal red cell osmotic fragility test result cannot exclude an osmotic fragility abnormality since the osmotically labile cells may be hemolyzed and not present. Recommend testing during a state of prolonged homeostasis with stable hematocrit.
Note
CPT Code(s)
85555
Components
Component Test Code*Component Chart Name
0049015Osmotic Fragility
2002142EER Osmotic Fragility
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • FRAGILITY, OSMOTIC (RBC)
  • Osmotic Fragility
  • RBC Fragility, Erythrocytes
  • Red Cell Fragility
  • Spherocytic Hemolytic Disease