Dehydroepiandrosterone, Serum or Plasma
Ordering Recommendation

Adjunct test for the investigation of hyperandrogenic and adrenal disorders. Not recommended for initial evaluation of polycystic ovarian syndrome.

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Collect between 6-10 a.m. 
Serum separator tube or green (sodium or lithium heparin). Also acceptable: Lavender (EDTA). 
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Unacceptable Conditions
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months 
Reference Interval
Effective August 19, 2013
PrematureLess than 40 ng/mLLess than 40 ng/mL
0-1 dayLess than 11 ng/mLLess than 11 ng/mL
2-6 daysLess than 8.7 ng/mLLess than 8.7 ng/mL
7 days-1 monthLess than 5.8 ng/mLLess than 5.8 ng/mL
1-5 monthsLess than 2.9 ng/mLLess than 2.9 ng/mL
6-24 monthsLess than 1.9 9 ng/mLLess than 2.5 ng/mL
2-3 yearsLess than 0.85 ng/mLLess than 0.63 ng/mL
4-5 yearsLess than 1.03 ng/mLLess than 0.95 ng/mL
6-7 yearsLess than 1.79 ng/mL0.06-1.93 ng/mL
8-9 years0.14-2.35 ng/mL0.10-2.08 ng/mL
10-11 years0.43-3.78 ng/mL0.32-3.08 ng/mL
12-13 years0.89-6.21 ng/mL0.57-4.10 ng/mL
14-15 years1.22-7.01 ng/mL0.93-6.04 ng/mL
16-17 years1.42-9.00 ng/mL1.17-6.52 ng/mL
18-39 years1.33-7.78 ng/mL1.33-7.78 ng/mL
40 years and older0.63-4.70 ng/mL0.63-4.70 ng/mL
Postmenopausal0.60-5.73 ng/mLDoes Not Apply
Tanner Stage I0.14-2.76 ng/mL0.11-2.37 ng/mL
Tanner Stage II0.83-4.87 ng/mL0.37-3.66 ng/mL
Tanner Stage III1.08-7.56 ng/mL0.75-5.24 ng/mL
Tanner Stage IV-V1.24-7.88 ng/mL1.22-6.73 ng/mL

Interpretive Data

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
Component Test Code*Component Chart NameLOINC
2001641Dehydroepiandrosterone by TMS2193-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • DHEA (Dehydroepiandrosterone, Serum or Plasma)
  • Unconjugated DHEA (Dehydroepiandrosterone, Serum or Plasma)