RNA Polymerase III Antibody, IgG
2001601
Ordering Recommendation
 
Mnemonic
RNA POL 3
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Tue, Thu, Sun
Reported
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
 
 
RNA Polymerase III Antibody, IgG
19 Units or less Negative
20-​39 Units Weak Positive
40-​80 Units Moderate Positive
81 Units or greater Strong Positive
Interpretive Data
Elevated RNA polymerase III IgG antibodies are found primarily in a subset of systemic sclerosis (SSc) patients who are typically negative for anti-centromere and anti-Scl-70 antibodies, and which may be predictive of increased risk for skin involvement and hypertensive renal failure associated with the diffuse cutaneous form of scleroderma.  
Note
 
CPT Code(s)
83516
Components
Component Test Code*Component Chart NameLOINC
2001602RNA Polymerase III Antibody, IgG63329-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • RNA pol 3
  • RNA Pol III IgG
  • RNA Polymerase III Ab