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Porphyrins, Fecal
0099824
Ordering Recommendation

Distinguish among acute intermittent porphyria (AIP), variegate porphyria (VP), and hereditary coproporphyria (HCP).

Mnemonic
POR FECES
Methodology
Quantitative High Performance Liquid Chromatography
Performed
Mon, Thu
Reported
2-7 days
+
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Random stool. 
Specimen Preparation
Protect from light during collection, storage, and shipment. Freeze specimen and wrap in foil immediately after collection. Transport 5 g stool. (Min: 1 g) 
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. 
Unacceptable Conditions
Complete timed collections (24-72 hour). Specimens stored in one gallon cans or other large containers. Liquid stool. 
Remarks
 
Stability
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 weeks 
Reference Interval
Test Number
Components
Reference Interval
 Coproporphyrin, Feces0-45 nmol/g dry weight
 Protoporphyrin, Feces0-100 nmol/g dry weight

Interpretive Data


Note
Bacterial modification of fecal porphyrins is extensive. The recommended specimen for uroporphyrin and coproporphyrin is urine (random or 24-hour). Refer to Porphyrins, Fractionation & Quantitation, Urine (ARUP test code 2002058). The recommended specimen for protoporphyrin is serum.  Refer to Porphyrins, Serum Total (ARUP test code 0080429). 
Components
Component Test Code*Component Chart NameLOINC
0020806Porphyrin Fecal Interpretation14884-1
0099825Protoporphyrin, Feces29267-2
0099826Coproporphyrin, Feces29266-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Coproporphyrinl
  • Coproporphyrins
  • Isocoproporphyrins
  • Protoporphyrin