Porphyrins, Fecal
0099824
Ordering Recommendation
Distinguish among acute intermittent porphyria (AIP) , variegate porphyria (VP), and hereditary coproporphyria (HCP).
Mnemonic
POR FECES
Methodology
Quantitative High Performance Liquid Chromatography
Performed
Mon, Thu
Reported
2-7 days
+
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Random stool.  
Specimen Preparation
Protect from light during collection, storage, and shipment. Freeze specimen and wrap in foil immediately after collection. Transport 5 g stool. (Min: 1 g)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Complete timed collections (24-72 hour). Specimens stored in one gallon cans or other large containers. Liquid stool.  
Remarks
  
Stability
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 weeks  
Reference Interval
 
 
Test Number Components Reference Interval
 Coproporphyrin0-​45 nmol/g dry weight
 Protoporphyrin0-​100 nmol/g dry weight
Interpretive Data
 
Note
Bacterial modification of fecal porphyrins is extensive. The recommended specimen for uroporphyrin and coproporphyrin is urine (random or 24-hour). Refer to Porphyrins, Fractionation & Quantitation, Urine (ARUP test code 2002058). The recommended specimen for protoporphyrin is serum.  Refer to Porphyrins, Serum Total (ARUP test code 0080429). 
CPT Code(s)
84126
Components
Component Test Code*Component Chart NameLOINC
0020806Porphyrin Fecal Interpretation14884-1
0099825Protoporphyrin, Feces29267-2
0099826Coproporphyrin, Feces29266-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Coproporphyrinl
  • Coproporphyrins
  • Isocoproporphyrins
  • Protoporphyrin