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ssDNA Antibody, IgG
0099528
Ordering Recommendation

Obsolete test for connective tissue disease; refer to IgG dsDNA reflex test 0050215, IgG dsDNA stand-alone test 2002693, or IgG chromatin 2005287.

Mnemonic
DNA SS
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Tue, Thu, Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum an ARUP Standard Transport Tube. (Min: 0.1 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Plasma. Contaminated, hemolyzed, or severely lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
< 20 EU: Negative
20-25 EU: Borderline positive
> 25 EU: Positive
Interpretive Data


Note
The ssDNA antibody test detects ssDNA and some dsDNA antibodies.  As a result, patient samples should also be tested for dsDNA antibodies in order to more accurately determine the level of anti-ssDNA antibodies.  By calculating the ratio (ssDNA/dsDNA), a conclusion can be made as to the presence of ssDNA antibodies.  A ratio less than or equal to 1.0 indicates the absence of ssDNA antibodies.  A ratio greater than 1.0 indicates the presence of ssDNA antibodies.
CPT Code(s)
86226
Components
Component Test Code*Component Chart NameLOINC
0099528ssDNA (Single-Stranded DNA) Ab, IgG10360-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Anti-ssDNA Antibody
  • Single Stranded DNA Antibody
  • SS DNA
  • ssDNA Antibody