Heavy Metals Panel 3, Blood
0099470
Ordering Recommendation
Mnemonic
HY MET B
Methodology
Quantitative Atomic Absorption/Quantitative Inductively Coupled Plasma-Mass Spectrometry
Performed
Mon-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
- Patient Preparation
- Collect
- Royal blue (K2EDTA or Na2EDTA).
- Specimen Preparation
- Transport 7 mL whole blood in the original collection tube. (Min: 1.5 mL)
- Storage/Transport Temperature
- Room temperature. Also acceptable: Refrigerated.
- Unacceptable Conditions
- Heparin anticoagulant. Frozen specimens.
- Remarks
- Lead requisition form may be required (ARUP form #32990-Barcode; #32991-No Barcode). Notification will be given if required.
- Stability
- Mercury is volatile; concentration may reduce after seven or more days of storage. If the specimen is drawn and stored in the appropriate container, the arsenic and lead values do not change with time.
Reference Interval
Interpretive Data
Information sources for reference intervals and interpretive comments include the "CDC Response to the 2012 Advisory Committee on Childhood Lead Poisoning Prevention Report" and the "Recommendations for Medical Management of Adult Lead Exposure, Environmental Health Perspectives, 2007." Thresholds and time intervals for retesting, medical evaluation, and response vary by state and regulatory body. Contact your State Department of Health and/or applicable regulatory agency for specific guidance on medical management recommendations.
Blood mercury levels predominantly reflect recent exposure and are most useful in the diagnosis of acute poisoning as blood mercury concentrations rise sharply and fall quickly over several days after ingestion. Blood concentrations in unexposed individuals rarely exceed 20 µg/L. The provided reference interval relates to inorganic mercury concentrations. Dietary and non-occupational exposure to organic mercury forms may contribute to an elevated total mercury result. Clinical presentation after toxic exposure to organic mercury may include dysarthria, ataxia and constricted vision fields with mercury blood concentrations from 20 to 50 µg/L.
Potentially toxic ranges for blood arsenic: Greater than or equal to 600 µg/L.
Blood arsenic is for the detection of recent exposure only. Blood arsenic levels in healthy subjects vary considerably with exposure to arsenic in the diet and the environment. A 24-hour urine arsenic is useful for the detection of chronic exposure.
Blood mercury levels predominantly reflect recent exposure and are most useful in the diagnosis of acute poisoning as blood mercury concentrations rise sharply and fall quickly over several days after ingestion. Blood concentrations in unexposed individuals rarely exceed 20 µg/L. The provided reference interval relates to inorganic mercury concentrations. Dietary and non-occupational exposure to organic mercury forms may contribute to an elevated total mercury result. Clinical presentation after toxic exposure to organic mercury may include dysarthria, ataxia and constricted vision fields with mercury blood concentrations from 20 to 50 µg/L.
Potentially toxic ranges for blood arsenic: Greater than or equal to 600 µg/L.
Blood arsenic is for the detection of recent exposure only. Blood arsenic levels in healthy subjects vary considerably with exposure to arsenic in the diet and the environment. A 24-hour urine arsenic is useful for the detection of chronic exposure.
Note
CPT Code(s)
82175; 83655; 83825
Components
| Component Test Code* | Component Chart Name |
|---|---|
| 0020098 | Lead, Blood (Venous) |
| 0099045 | Arsenic Blood |
| 0099305 | Mercury Blood |
Cross References
- Arsenic (As) (Heavy Metals Panel 3, Blood)
- Lead (Pb) (Heavy Metals Panel 3, Blood)
- Mercury (Hg) (Heavy Metals Panel 3, Blood)