Manganese, Whole Blood
Ordering Recommendation
Useful as a reasonable indicator of recent, active exposure and provides a modest indicator for distinguishing exposed from nonexposed individuals. Recommended for monitoring potential accumulation with TPN. Not recommended for detecting long-term, low-dose manganese exposure, refer to Manganese, RBC (2007254).
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Tue, Fri
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Diet, medication, and nutritional supplements may introduce interfering substances. Patient should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).  
Royal blue (K2EDTA or Na2EDTA).  
Specimen Preparation
Transport 7 mL whole blood in the original collection tube. (Min: 1 mL)  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated.  
Unacceptable Conditions
Heparin anticoagulant. Clotted specimens.  
If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time. Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
4.2-16.5 µg/L  
Interpretive Data

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Elevated results from noncertified trace element-free collection tubes may be due to contamination.  Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na2EDTA) tube.
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0099272Manganese, Blood5681-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Mn
  • Mn,WB
  • MNB