Cobalt, Blood
0099231
Ordering Recommendation
Submit With Order
Mnemonic
COBALT B
Methodology
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Performed
Tue, Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).  
Collect
Royal blue (K2EDTA or Na2EDTA).  
Specimen Preparation
Transport 7 mL whole blood in the original collection tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated.  
Unacceptable Conditions
Heparin anticoagulant. Frozen specimens.  
Remarks
 
Stability
If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.  
Reference Interval
0.5-3.9 µg/L
Interpretive Data
Blood cobalt levels can be used in the assessment of occupational exposure or toxic ingestion. Symptoms associated with cobalt toxicity vary based on route of exposure and may include cardiomyopathy, allergic dermatitis, pulmonary fibrosis, cough and dyspnea. Serum is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty.
Note
Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na2EDTA) tube.
CPT Code(s)
83018
Components
Component Test Code*Component Chart Name
0099231Cobalt Blood
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Blood cobalt concentration
  • Co
  • COB