Quantitative Inductively Coupled Plasma-Mass Spectrometry
This test is New York DOH approved.
- Patient Preparation
- Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).
- Royal blue (K2EDTA or Na2EDTA).
- Specimen Preparation
- Transport 7 mL whole blood in the original collection tube. (Min: 0.5 mL)
- Storage/Transport Temperature
- Room temperature. Also acceptable: Refrigerated.
- Unacceptable Conditions
- Heparin anticoagulant. Frozen specimens.
- If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.
Blood cobalt levels can be used in the assessment of occupational exposure or toxic ingestion. Symptoms associated with cobalt toxicity vary based on route of exposure and may include cardiomyopathy, allergic dermatitis, pulmonary fibrosis, cough and dyspnea. Serum is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty.
Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue (Na2EDTA) tube.
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- Blood cobalt concentration