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Tryptase
0099173
Ordering Recommendation

Measure total tryptase to confirm mast cell activation in diseases such as mastocytosis, anaphylaxis, urticaria, and asthma. Not generally used acutely except where diagnosis is unclear. Useful in prognosis of systemic mastocytosis.

Mnemonic
TRYPT
Methodology
Quantitative Fluorescent Enzyme Immunoassay
Performed
Mon, Wed, Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Allow serum to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 72 hours; Frozen: 1 month 
Reference Interval
Less than 11.0 µg/L
Interpretive Data


Note
This test measures total tryptase and does not distinguish between the alpha and beta protein types. Samples should preferably be collected between 15 minutes and three hours after the event suspected to have caused mast cell activation.
Hotline History
N/A
CPT Code(s)
83520
Components
Component Test Code*Component Chart NameLOINC
0099173Tryptase21582-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Total Tryptase
  • Tryptase, Autopsy (Tryptase)