Tryptase
0099173
Ordering Recommendation
Measure total tryptase to confirm mast cell activation in diseases such as
• Mastocytosis
• Anaphylaxis
• Urticaria
•Asthma
Not generally used acutely except where diagnosis is unclear. Useful in prognosis of systemic mastocytosis.
Mnemonic
TRYPT
Methodology
Quantitative Fluorescent Enzyme Immunoassay
Performed
Mon, Wed, Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
- Patient Preparation
- Collect
- Serum separator tube.
- Specimen Preparation
- Allow serum to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
- Storage/Transport Temperature
- Frozen.
- Unacceptable Conditions
- Remarks
- Stability
- After separation from cells: Ambient: 48 hours; Refrigerated: 72 hours; Frozen: 1 month
Reference Interval
Less than 11.0 µg/L
Interpretive Data
Note
This test measures total tryptase and does not distinguish between the alpha and beta protein types. Samples should preferably be collected between 15 minutes and three hours after the event suspected to have caused mast cell activation.
CPT Code(s)
83520
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0099173 | Tryptase | 21582-2 |
Aliases
- Total Tryptase
- Tryptase, Autopsy (Tryptase)