Protein S Free, Antigen
0098894
Ordering Recommendation
Recommended test to detect protein S deficiency. Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
Mnemonic
PRO S FREE
Methodology
Microlatex Particle-Mediated Immunoassay
Performed
Mon-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
- Patient Preparation
- Collect
- Light Blue (Sodium Citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
- Specimen Preparation
- Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
- Storage/Transport Temperature
- CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
- Unacceptable Conditions
- Serum. EDTA plasma, clotted or hemolyzed specimens.
- Remarks
- Stability
- Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months
Reference Interval
| Age | Male | Female |
|---|---|---|
| 1-89 days | 15-55% | 15-55% |
| 90-179 days | 35-92% | 35-92% |
| 180-364 days | 45-115% | 45-115% |
| 1-5 years | 62-120% | 62-120% |
| 6-9 years | 62-130% | 62-130% |
| 10-17 years | 60-140% | 60-140% |
| 18 years and older | 74-147% | 55-123% |
Interpretive Data
Patients on warfarin may have decreased free protein S values. Patients should be off warfarin therapy for two weeks for accurate measurement of free protein S levels. Decreased levels of free protein S are also associated with DIC, liver disease, pregnancy, and inflammatory syndromes.
Note
CPT Code(s)
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0098894 | Protein S Ag Free | 27821-8 |
Aliases