Protein S Free, Antigen
0098894
Ordering Recommendation
Recommended test to detect protein S deficiency. Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
Mnemonic
PRO S FREE
Methodology
Microlatex Particle-Mediated Immunoassay
Performed
Mon-Sat
Reported
1-3 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.   
Unacceptable Conditions
Serum. EDTA plasma or hemolyzed specimens.  
Remarks
 
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months  
Reference Interval
 
 
Age Male Female
1-​89 days 15-​55% 15-​55%
90-​179 days 35-​92% 35-​92%
180-​364 days 45-​115% 45-​115%
1-​5 years 62-​120% 62-​120%
6-​9 years 62-​130% 62-​130%
10-​17 years 60-​140% 60-​140%
18 years and older 74-​147% 55-​123%
Interpretive Data
Patients on warfarin may have decreased free protein S values. Patients should be off warfarin therapy for two weeks for accurate measurement of free protein S levels. Decreased levels of free protein S are also associated with DIC, liver disease, pregnancy, and inflammatory syndromes.  
Note
 
CPT Code(s)
85306
Components
Component Test Code*Component Chart NameLOINC
0098894Protein S Ag Free27821-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases