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Protein S Free, Antigen
0098894
Ordering Recommendation
Recommended test to detect protein S deficiency. Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
Mnemonic
PRO S FREE
Methodology
Microlatex Particle-Mediated Immunoassay
Performed
Mon-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.   
Unacceptable Conditions
Serum. EDTA plasma, clotted or hemolyzed specimens.  
Remarks
 
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months  
Reference Interval
AgeMaleFemale
1-89 days15-55%15-55%
90-179 days35-92%35-92%
180-364 days45-115%45-115%
1-5 years62-120%62-120%
6-9 years62-130%62-130%
10-17 years60-140%60-140%
18 years and older74-147%55-123%

Interpretive Data
Patients on warfarin may have decreased free protein S values. Patients should be off warfarin therapy for two weeks for accurate measurement of free protein S levels. Decreased levels of free protein S are also associated with DIC, liver disease, pregnancy, and inflammatory syndromes.


Note
CPT Code(s)
85306
Components
Component Test Code*Component Chart NameLOINC
0098894Protein S Ag Free27821-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases