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Cardiolipin Antibody, IgA
0098358
Ordering Recommendation

Preferred second-line testing for strong suspicion of seronegative antiphospholipid syndrome (APS). Order incrementally or concurrently with other non-criteria antiphospholipid antibody tests.

Mnemonic
CARDIO IGA
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Effective August 18, 2014
0-11 APL: Negative
12-19 APL: Indeterminate
20-80 APL: Low to Moderately Positive
81 APL or above: High Positive
Interpretive Data


Note
APL = IgA phospholipid units.
CPT Code(s)
86147
Components
Component Test Code*Component Chart NameLOINC
0098358Cardiolipin Antibody IgA5076-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ACA
  • aCL Antibody
  • aCL IgA
  • Anticardiolipin Antibodies
  • Cardiolip