Zonisamide
0097908
Ordering Recommendation
 
Mnemonic
ZONI
Methodology
Quantitative Enzyme Multiplied Immunoassay Technique
Performed
Mon-Fri
Reported
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.  
Collect
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).  
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated  
Unacceptable Conditions
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).  
Remarks
  
Stability
After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 6 weeks  
Reference Interval
Effective February 19, 2013
 
Therapeutic Range Not well established
Toxic Level Greater than 80 µg/mL
Interpretive Data
The proposed therapeutic range for seizure control is 10-40 µg/mL. Toxic concentrations may cause coma, seizures and cardiac abnormalities. Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function.  
Note
 
CPT Code(s)
80203
Components
Component Test Code*Component Chart NameLOINC
0097908Zonisamide Quantitative29620-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Excegran
  • Zonegran
  • zonegran blood level
  • zonegran concentration
  • zonisamide blood concentration