Anaplasma phagocytophilum (HGA) Antibodies, IgG and IgM
Ordering Recommendation
Acceptable test for acute or convalescent phase of infection from Anaplasma phagocytophilium. May be useful when PCR testing is not an option (eg, outside the 2 week window for acute phase). However, PCR testing is generally preferred; refer to Tick-Borne Disease Panel by PCR, Blood (2008670) or Ehrlichia and Anaplasma Species by Real-Time PCR (2007862).
Semi-Quantitative Indirect Fluorescent Antibody
Tue, Fri
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Serum separator tube.  
Specimen Preparation
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.05 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.  
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
0097317Anaplasma phagocytophilum (HGA) Antibody, IgG Less than 1:80 -​ No significant level of IgG antibodies to A. phagocytophilum detected.
Greater than or equal to 1:80 -​ Suggestive of a recent or past infection with A. phagocytophilum
0097318Anaplasma phagocytophilum (HGA) Antibody, IgM Less than 1:16 -​ No significant level of IgM antibodies to A. phagocytophilum detected.
Greater than or equal to 1:16 -​ Suggestive of a current or recent infection with A. phagocytophilum.
Interpretive Data

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
CPT Code(s)
86666 x2
Component Test Code*Component Chart NameLOINC
0097317A. Phagocytophilum Antibody, IgG23877-4
0097318A. Phagocytophilum Antibody, IgM23878-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • A. phagocytophilum IgG, IgM
  • Anaplasma phagocytophilum
  • Ehrlichiosis Serology
  • HGE
  • Human Granulocytic Anaplasmosis (HGA)
  • Human Granulocytic Ehrlichiosis (HGE)
  • Phagocytophilum Titer