Ordering Recommendation

Acceptable test for acute or convalescent phase of infection from Anaplasma phagocytophilium. May be useful when PCR testing is not an option (eg, outside the 2 week window for acute phase). However, PCR testing is generally preferred; refer to Tick-Borne Disease Panel by PCR, Blood (2008670) or Ehrlichia and Anaplasma Species by PCR (2007862).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.4 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Semi-Quantitative Indirect Fluorescent Antibody (IFA)

Performed

Tue, Fri

Reported

1-5 days

Reference Interval

Test Number
Components
Reference Interval
  A. Phagocytophilum Antibody, IgG Less than 1:80
  A. Phagocytophilum Antibody, IgM Less than 1:16

Interpretive Data




Component Interpretation
Anaplasma phagocytophilum (HGA) Antibody, IgG Less than 1:80 - No significant level of IgG antibodies to A. phagocytophilum detected.
Greater than or equal to 1:80 - Suggestive of a recent or past infection with A. phagocytophilum
phagocytophilum (HGA) Antibody, IgM Less than 1:16 - No significant level of IgM antibodies to A. phagocytophilum detected.
Greater than or equal to 1:16 - Suggestive of a current or recent infection with A. phagocytophilum.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

86666 x2

Components

Component Test Code* Component Chart Name LOINC
0097317 A. Phagocytophilum Antibody, IgG 23877-4
0097318 A. Phagocytophilum Antibody, IgM 23878-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • A. phagocytophilum IgG, IgM
  • Anaplasma phagocytophilum
Anaplasma phagocytophilum (HGA) Antibodies, IgG and IgM