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Leukemia/Lymphoma Phenotyping (Comprehensive - Whole Blood) (INACTIVE as of 05/20/13: Refer to 2008003.)
0096299
Ordering Recommendation
Mnemonic
LEUK-WB
Methodology
Flow Cytometry
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Flow Cytometry Test Request Form RecommendedFlow Cytometry Test Request Form Recommended
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Green (sodium heparin), lavender (EDTA), or pink (K2EDTA). 
Specimen Preparation
Transport 5 mL whole blood. 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Specimen should be received within 24 hours of collection for optimal viable testing. 
Unacceptable Conditions
Frozen specimens. Clotted or hemolyzed specimens. Specimens greater than 48 hours old. 
Remarks
Provide CBC, Wright's stained smear, clinical history, differential diagnosis, and any relevant pathology reports. 
Stability
Ambient: 48 hours; Refrigerated: 48 hours; Frozen Unacceptable 
Reference Interval
By report

Available Antigens Included:
*Not all markers will be reported in all cases.  Requests for specific markers to be included must be listed on manual requisition or by footnote for electronic orders.  We do not offer individual markers without also running our panel.

T-cell: CD1, CD2, CD3, CD4, CD5, CD7, CD8, TCR alpha-beta, TCR gamma-delta, Cytoplasmic CD3
B-cell:
CD10, CD19, CD20, CD22, CD23, CD103, Kappa, Lambda, FMC7, Cytoplasmic Kappa, Cytoplasmic Lambda
Myelo/Mono:
CD11b, CD13, CD14 (Mo2), CD14 (MY4), CD15, CD33, CD64, CD117, myeloperoxidase
Misc:
CD11c, CD16, CD25, CD30, CD34, CD38, CD41, CD42b, CD45, CD56, CD57, CD61, HLA-DR, glycophorin, TdT, bcl-2
Interpretive Data


Compliance Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.

Note
Surface markers in leukemia and lymphoma may aid in identifying the tumor lineage for diagnostic and prognostic purposes. After review of the clinical history and morphology, a panel of markers is selected for each case by a board-certified pathologist. In most cases, the lineage can be identified as T-cell, B-cell, or myeloid and a diagnosis, or differential diagnosis, can be made.
CPT Code(s)
88184 First marker and 88185 Each additional marker; AND 88187 Interpretation for 2-8 markers or 88188 Interpretation for 9-15 markers or 88189 Interpretation for 16 or more markers.
Components
Component Test Code*Component Chart NameLOINC
0092286Number Of Markers19099-1
0095234Interpretation50595-8
0096200% CD28118-2
0096201% CD38124-0
0096202% bcl-2
0096203% CD48123-2
0096204% CD58132-3
0096205% CD78135-6
0096206% CD88101-8
0096207% CD258121-6
0096209% CD168115-8
0096210% CD568133-1
0096211% CD578134-9
0096212% CD108107-5
0096213% CD198117-4
0096214% CD208119-0
0096215% CD218120-8
0096216% CD2214017-8
0096217% CD2314018-6
0096218% CD2417126-4
0096219% Kappa17096-9
0096220% Lambda17224-7
0096221% CD10317100-9
0096222% CD11c8109-1
0096223% FMC717220-5
0096224% CD79b17197-5
0096225% CD11b17110-8
0096226% CD138110-9
0096227% CD14 (MO2)8111-7
0096228% CD14 (MY4)8111-7
0096229% CD1517117-3
0096230% CD338102-6
0096231% CD388126-5
0096232% CD348125-7
0096233% HLA-DR31113-4
0096234% TdT
0096236% CD6417183-5
0096237% Alpha-Beta
0096238% Gamma-Delta
0096244% CD1817121-5
0096245% CDw65
0096246% CD11717107-4
0096247% Myeloperoxidase
0096248% CD9
0096249% CD4117148-8
0096250% CD42b17150-4
0096251% CD6120478-4
0096252% CD3017137-1
0096253% CD18106-7
0096254% Glycophorin17221-3
0096255% Cytoplasmic CD317216-3
0096256% Cytoplasmic Kappa
0096257% Cytoplasmic Lambda
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases