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Lymphocyte Transplantation CD3
0095949
Ordering Recommendation

Monitor response to CD3 immunosuppressive therapy.

Mnemonic
CD3
Methodology
Quantitative Flow Cytometry
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Time SensitiveTime Sensitive
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Draw specimen before administering immunosuppressive medications. 
Collect
Green (Sodium or Lithium Heparin), Lavender (EDTA), or Pink (K2EDTA). 
Specimen Preparation
Transport 5 mL whole blood. (Min: 0.5 mL) 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. 
Unacceptable Conditions
Clotted or hemolyzed specimens. 
Remarks
Specimens must be analyzed within 72 hours of collection.
New York State Clients: EDTA specimens must be analyzed within 30 hours of collection. Heparin specimens must be analyzed within 48 hours of collection. 
Stability
Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable
New York State Clients: EDTA: Ambient: 30 hours; Refrigerated: 30 hours; Frozen: Unacceptable
Heparin: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable 
Reference Interval
Effective February 20, 2018
Components
17 years and older
%CD356-85 %
Abs CD3633-2532 cells/µL

Interpretive Data
In this test, the percent CD3 cells are those cells that are positive for both CD3 and the alpha-beta chain of the T-cell receptor and are presumed immunologically competent.

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Note
THIS TEST IS FOR TRANSPLANT PATIENTS ONLY.  Effective immunosuppressive therapy with OKT3 can be documented by verifying CD3 antigen removal using this test.  For immunocompromised patients, order Lymphocyte Subset Panel 4 - T-Cell subsets Percent & Absolute (0095950).
Hotline History
View Hotline History
Components
Component Test Code*Component Chart NameLOINC
0095248% CD3+/A-B+8124-0
0095249Absolute CD3+/A-B+8122-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CD3 absolute
  • immunosuppresive therapy monitoring