Lymphocyte Transplantation Profile
0095798
Ordering Recommendation
Intended for TRANSPLANT patients only.
Mnemonic
LYMPHPRO
Methodology
Quantitative Flow Cytometry
Performed
Sun-Sat
Reported
Within 24 hours  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Time SensitiveTime Sensitive

Specimen Required
Patient Preparation
Draw specimen before administering immunosuppressive medications.  
Collect
Green (sodium or lithium heparin), lavender (EDTA) or pink (K2EDTA).   
Specimen Preparation
Transport 5 mL whole blood. (Min: 1 mL)  
Storage/Transport Temperature
CRITICAL ROOM TEMPERATURE.  
Unacceptable Conditions
Clotted, hemolyzed, frozen, or refrigerated specimens. Specimens older than 48 hours.
New York State Clients:
 
Clotted, hemolyzed, frozen, or refrigerated specimens. EDTA specimens older than 30 hours and heparin specimens older than 48 hours.  
Remarks
Specimens must be analyzed within 48 hours of collection. Some medications may affect immunophenotyping results and should be listed on the patient test request form.
THIS TEST IS FOR TRANSPLANT PATIENTS ONLY. WBC and lymphocyte percent results with the same draw date and time as the Lymphocyte Transplantation Profile specimen must be provided by client.
New York State Clients:
 
EDTA specimens must be analyzed within 30 hours of collection.  Heparin specimens must be analyzed within 48 hours of collection.  
Stability
Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
New York State Clients:
Ambient: 30 hours in EDTA, 48 hours in heparin; Refrigerated: Unacceptable; Frozen: Unacceptable  
Reference Interval
Effective November 18, 2013
Reports include age appropriate reference intervals and interpretation.
 
Components 0-​11 months 12-​23 months 2 years and older
% CD2 55-​88 % 55-​88 % 72-​93 %
Absolute CD2 3800-​5300 cells/µL 3100-​4200 cells/µL 820-​2800 cells/µL
% CD3 58-​85 % 53-​81 % 59-​86 %
Abs CD3 2170-​6500 cells/µL 1460-​5440 cells/µL 650-​2500 cells/µL
% CD4 38-​62 % 31-​54 % 30-​63 %
% CD8 16-​34 % 16-​38 % 14-​46 %
CD4: CD8 ratio 1.17-​6.62 1.17-​6.62 0.70-​4.00
% CD19 11-​45 % 11-​45 % 6-​23 %
Interpretive Data
In this test, the percent CD3 cells are those cells that are positive for both CD3 and the alpha-beta chain of the T-cell receptor and are presumed immunologically competent.

See Compliance Statement A: www.aruplab.com/CS  
Note
Immunosuppressive therapy with anti-lymphocyte drugs, such as OKT3 or ATG (anti-thymocyte globulin), can be monitored with this test.  For immunocompromised patients, order Lymphocyte Subset Panel 5 - Total Lymphocyte Enumeration (ARUP test code 0095892).
CPT Code(s)
86356 x6
Components
Component Test Code*Component Chart Name
0095248% CD3+/A-B+
0095249Absolute CD3+/A-B+
0095905% CD4
0095910% CD8
0095914% CD19
0095920CD4:CD8 Ratio
0095930% CD2
0095931Absolute CD2
0097135White Blood Cell Count
0097140% Lymph
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Immunosuppressive therapy monitoring
  • Post Transplant CD2 and CD3 Monitoring, Percent and Absolute