Treponema pallidum (VDRL), Serum with Reflex to Titer
0093093
Ordering Recommendation
Acceptable initial screening test for syphilis. May use to confirm reactive treponemal test (eg, EIA, CIA) if using so-called reverse algorithm testing. Acceptable test for monitoring treatment response in established syphilis.
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Mnemonic
VDRL SERU
Methodology
Semi-Quantitative Flocculation
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Plain red or serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube (Min: 0.25 mL)  
Storage/Transport Temperature
Refrigerated  
Unacceptable Conditions
CSF or other body fluids. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
Treponema pallidum (VDRL), Serum Nonreactive
Treponema pallidum (VDRL) Titer, Serum Effective February 18, 2014
Non-​reactive
Interpretive Data
VDRL as a screening test is less sensitive than RPR.
Note
If VDRL is reactive, then a titer will be added. Additional charges apply.
CPT Code(s)
86592; if reflexed, add 86593
Components
Component Test Code*Component Chart Name
0093094Treponema pallidum (VDRL) Titer, Serum
0098975Treponema pallidum (VDRL), Serum
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Syphilis, Serum
  • Treponema pallidum, Serum
  • VDRL Reflex to titer
  • VDRL, Serum