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Cutaneous Direct Immunofluorescence, Biopsy
0092572
Ordering Recommendation
•Order concurrently with serum antibody testing and fixed tissue histopathology for assessment of patient with pruritic, urticarial, blistering and/or erosive disorders, including possible pemphigoid and pemphigoid variants, pemphigus and pemphigus subtypes, dermatitis herpetiformis, epidermolysis bullous acquisita, porphyria, and pseudoporphyria.
•Order concurrently with fixed tissue histopathology for assessment of patient with inflammatory, immune-mediated cutaneous disease, including possible lupus and lupus variants, vasculitis, drug reactions, lichen planus and lichenoid reactions.
Mnemonic
CUTDIF
Methodology
Direct Immunofluorescence
(Direct Fluorescent Antibody Stain)
Performed
Varies
Reported
3-7 days  
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
  
Collect
Tissue, skin, or mucous membrane.  
Specimen Preparation
Transport epidermis/epithelium and dermis tissue (optimal 4-5 mm) in Michel's Media (ARUP supply #45462) available online through eSupply using ARUP Connect™ or call ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Formalin-fixed tissue.  
Remarks
  
Stability
Ambient: 10 days; Refrigerated: 10 days; Frozen: Unacceptable  
Reference Interval
By report  
Interpretive Data
 
Note
 
CPT Code(s)
88346 x5
Components
Component Test Code*Component Chart NameLOINC
0092571Cutaneous Direct IF, Biopsy6471-7
2010916EER Cutaneous Direct IF, Biopsy 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Bullous Disease
  • Chronic Bullous Disease
  • Cutaneous Herpetiformis
  • Dermatitis Herpetiformis
  • Lichen Planus and Lichenoid
  • Linear IgA Bullous, Tissue
  • Lupus Erythematous, Tissue
  • Pemphigoid, Tissue
  • Pemphigus
  • Porphyria and Pseudoporphyria, Tissue
  • Skin Immunofluorescence
  • Urticaria
  • Urticarial Pemphigoid
  • Urticarial Vasculitis
  • Vasculitis

Performed at UUHC-Immunodermatology