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Cutaneous Direct Immunofluorescence, Biopsy
0092572
Ordering Recommendation
- Order concurrently with serum antibody testing and fixed tissue histopathology for assessment of patient with pruritic, urticarial, blistering and/or erosive disorders, including possible pemphigoid and pemphigoid variants, pemphigus and pemphigus subtypes, dermatitis herpetiformis, epidermolysis bullous acquisita, porphyria, and pseudoporphyria.
- Order concurrently with fixed tissue histopathology for assessment of patient with inflammatory, immune-mediated cutaneous disease, including possible lupus and lupus variants, vasculitis, drug reactions, lichen planus and lichenoid reactions.
Mnemonic
CUTDIF
Methodology
Direct Immunofluorescence
(Direct Fluorescent Antibody Stain)
Performed
Varies
Reported
3-7 days  
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
  
Collect
Tissue, skin, or mucous membrane.  
Specimen Preparation
Transport epidermis/epithelium and dermis tissue (optimal 4-5 mm) in Michel's Media (ARUP supply #45462) available online through eSupply using ARUP Connect™ or call ARUP Client Services at (800) 522-2787.  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Formalin-fixed tissue.  
Remarks
  
Stability
Ambient: 10 days; Refrigerated: 10 days; Frozen: Unacceptable  
Reference Interval
By report  
Interpretive Data
 
Note
 
CPT Code(s)
88346 x5
Components
Component Test Code*Component Chart NameLOINC
0092571Cutaneous Direct IF, Biopsy6471-7
2010916EER Cutaneous Direct IF, Biopsy 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Bullous Disease
  • Chronic Bullous Disease
  • Cutaneous Herpetiformis
  • Dermatitis Herpetiformis
  • Lichen Planus and Lichenoid
  • Linear IgA Bullous, Tissue
  • Lupus Erythematous, Tissue
  • Pemphigoid, Tissue
  • Pemphigus
  • Porphyria and Pseudoporphyria, Tissue
  • Skin Immunofluorescence
  • Urticaria
  • Urticarial Pemphigoid
  • Urticarial Vasculitis
  • Vasculitis

Performed at UUHC-Immunodermatology