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Drug Screen 9 Panel, Serum or Plasma - Immunoassay Screen with Reflex to Mass Spectrometry Confirmation/Quantitation
0092420
Ordering Recommendation

Monitor patient compliance.

Mnemonic
DRUG SCRSP
Methodology
Qualitative Enzyme-Linked Immunosorbent Assay/ Quantitative Gas Chromatography-Mass Spectrometry/Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-2 days
Confirmation: 1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Gray (sodium fluoride/potassium oxalate). Also acceptable: Plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA). 
Specimen Preparation
Remove plasma from cells ASAP or within 2 hours of collection. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 3 mL) Also acceptable: Serum. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Specimens exposed to repeated freeze/thaw cycles. Separator tubes. Plasma or whole blood collected in lt. blue (sodium citrate). 
Remarks
Cocaine and cocaethylene are more stable in fluoride-preserved plasma than serum. 
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years 
Reference Interval
Drugs Covered and Cutoff Concentrations
Drugs/Drug Classes
Screen
Amphetamines30 ng/mL
Methamphetamine30 ng/mL
Barbiturates75 ng/mL
Benzodiazepines75 ng/mL
BuprenorphineEffective Aug 15, 2016
1 ng/mL
Cannabinoids30 ng/mL
Cocaine30 ng/mL
Methadone40 ng/mL
Opiates30 ng/mL
Oxycodone30 ng/mL
Phencyclidine15 ng/mL

Interpretive Data
Drugs/Drug classes reported as "Positive" are automatically reflexed to mass spectrometry confirmation/quantitation. An unconfirmed positive immunoassay screen result may be useful for medical purposes but does not meet forensic standards. The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies within a drug class. Specimens for which drugs or drug classes are detected by the screen are automatically reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Screen-positive specimens are automatically confirmed by GC/MS and/or LC-MS/MS; additional charges may apply.
CPT Code(s)
80301; if positive, add appropriate CPT code(s): 80324; 80359; 80345; 80346; 80349; 80353; 80358; 80361; 80365; 80348; 83992 (Alt code: G0479; if positive, add appropriate CPT code(s): G0480)
Components
Component Test Code*Component Chart NameLOINC
0092419Drug Screen Comments, Serum or Plasma48767-8
0092421Cannabinoids, S/P, Screen8172-9
0092422Cocaine, S/P, Screen8191-9
0092423Opiates, S/P, Screen8219-8
0092424Phencyclidine, S/P, Screen8236-2
0092425Amphetamines, S/P, Screen8149-7
0092426Barbiturates, S/P, Screen20421-4
0092427Benzodiazepines, S/P, Screen46976-7
0092428Methadone, S/P, Screen59705-4
0092430Oxycodone, S/P, Screen13576-4
0093414Methamphetamine, S/P, Screen3777-0
2013568Buprenorphine, S/P, Screen3413-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Pain Management