ZAP-70 Analysis by Flow Cytometry
Additional Technical InformationAdditional Technical Information

Flow Cytometry Test Request Form RecommendedFlow Cytometry Test Request Form Recommended

Ordering Recommendation
Determines risk group in newly diagnosed CLL.
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Flow Cytometry
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Green (sodium heparin). Also acceptable: Lavender (EDTA) or pink (K2EDTA).  
Specimen Preparation
Transport 5 mL whole blood.  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. Specimen should be received within 24 hours of collection for optimal viable testing.  
Unacceptable Conditions
Frozen specimens. Clotted or hemolyzed specimens. Specimens greater than 48 hours old.  
Prior diagnosis of CLL is required. Provide CBC results and Wright's stained smear, if available.  
Ambient: 24 hours; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
By report
Interpretive Data
ZAP-70 results should not be used for diagnostic purposes, but may help in the clinical management of patients with established diagnoses of chronic lymphocytic leukemia. Results of this test should always be correlated with morphologic and clinical information.

See Compliance Statement A:
CPT Code(s)
88184 First marker; 88185x2 Additional markers; 88187 Interpretation of 2-8 markers
Component Test Code*Component Chart Name
0092386ZAP-70 Analysis
0092387CD19 + Lymphocytes
0092388CD5 + CD19 - Lymphocytes
0092389CD5 + CD19 + Lymphocytes
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Zeta Associated Protein
  • Chronic Lymphocytic Leukemia Prognosis
  • CLL Prognosis
  • ZAP 70
  • ZAP-70 in B-CLL ( Chronic Lymphocytic Leukemia) Prognosis