11-Deoxycortisol Quantitative by HPLC-MS/MS, Serum or Plasma
Ordering Recommendation
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Mon, Wed, Fri
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube. Also acceptable: Plain red, pink (K2EDTA), plasma separator tube, green (sodium heparin), or green (lithium heparin). 
Specimen Preparation
Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) 
Storage/Transport Temperature
Refrigerated. Also acceptable: Frozen. 
Unacceptable Conditions
Grossly hemolyzed specimens. 
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months 
Reference Interval
Effective August 19, 2013
Premature (26-28 weeks)110-1376 ng/dL110-1376 ng/dL
Premature (29-36 weeks)70-455 ng/dL70-455 ng/dL
Full Term (1-5 months)10-200 ng/dL10-200 ng/dL
6-11 months10-276 ng/dL10-276 ng/dL
1-3 years7-247 ng/dL7-202 ng/dL
4-6 years8-291 ng/dL8-235 ng/dL
7-9 yearsLess than or equal to 94 ng/dLLess than or equal to 120 ng/dL
10-12 yearsLess than or equal to 123 ng/dLLess than or equal to 92 ng/dL
13-15 yearsLess than or equal to 107 ng/dLLess than or equal to 95 ng/dL
16-17 yearsLess than or equal to 47 ng/dLLess than or equal to 106 ng/dL
18 years and olderLess than 33 ng/dLLess than 50 ng/dL
Tanner Stage ILess than or equal to 94 ng/dLLess than or equal to 105 ng/dL
Tanner Stage IILess than or equal to 136 ng/dLLess than or equal to 108 ng/dL
Tanner Stage IIILess than or equal to 99 ng/dLLess than or equal to 111 ng/dL
Tanner Stage IV & VLess than or equal to 50 ng/dLLess than or equal to 83 ng/dL
After metyrapone stimulationGreater than 8000 ng/dLGreater than 8000 ng/dL

Interpretive Data

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
Component Test Code*Component Chart NameLOINC
009233111-Deoxycortisol, HPLC-MS/MS1657-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • 11-deoxy-17-Hydroxycorticosterone
  • Cortodoxone